Shohat M, Shohat T, Kedem R, Mimouni M, Danon Y L
Arch Dis Child. 1987 Jan;62(1):63-5. doi: 10.1136/adc.62.1.63.
To study the ultimate growth variables of children with asthma we analysed the military medical records of 54,041 boys and 38,102 girls at the age of 17 years. History of asthma was found in 2252 boys and 1158 girls, who were then categorised according to three grades of severity. Analysis of their growth was made separately for each sex and for each grade of severity of clinical disease. Boys who suffered from mild asthma that subsided before adolescence were significantly taller, heavier, and fatter than their respective controls. There was a slight decrement in all three growth variables in correlation with increased severity. The most severely affected patients had retarded height and weight in comparison with the mildly affected children, but the differences were not significant. The same tendency was found in the girls. Children with asthma will ultimately reach normal height and weight. Those who are mildly affected tend to be even taller and heavier than adolescents without asthma. The severity of the asthma influences final growth.
为研究哮喘患儿的最终生长变量,我们分析了54041名17岁男孩和38102名17岁女孩的军事医疗记录。在2252名男孩和1158名女孩中发现有哮喘病史,然后根据严重程度分为三个等级。对每个性别和临床疾病的每个严重程度等级分别进行生长分析。青春期前病情缓解的轻度哮喘男孩比各自的对照组明显更高、更重、更胖。随着病情严重程度增加,所有三个生长变量均略有下降。与轻度受影响的儿童相比,受影响最严重的患者身高和体重发育迟缓,但差异不显著。女孩中也发现了同样的趋势。哮喘患儿最终将达到正常身高和体重。轻度受影响的患儿往往比没有哮喘的青少年更高、更重。哮喘的严重程度会影响最终生长。