Descy J, De Mol P, Hayette M P, Huynen P, Meex C, Melin P
Department of Medical Microbiology, University of Liège (ULg), Liège, Belgium.
Acta Clin Belg. 2012 Jul-Aug;67(4):295-7. doi: 10.2143/ACB.67.4.2062676.
Listeriosis, an opportunistic food-borne disease caused by Listeria monocytogenes, is infrequent and occurs preferentially in patients at the extremes of age, during pregnancy or in immunocompromised hosts. Most common manifestations are maternofoetal and neonatal infections, severe invasive presentations such as bacteraemia with or without central nervous system symptoms occuring preferentially in immunosuppressed patients and self-limited gastro-enteritis affecting healthy individuals. Exceptionally, focal infections such as cholecystitis are described. We report here a case of acute cholecystitis caused by Listeria monocytogenes in an 82-year-old woman. Thanks to a successful treatment: cholecystectomy and antimicrobial therapy (amoxicillin plus clavulanic acid), the patient soon recovered. This case-report provides an opportunity to review the current literature concerning the association of Listeria monocytogenes and cholecystitis.
李斯特菌病是一种由单核细胞增生李斯特菌引起的食源性机会性疾病，较为罕见，主要发生于年龄极端的患者、孕期妇女或免疫功能低下的宿主。最常见的表现是母婴和新生儿感染，严重的侵袭性表现，如伴有或不伴有中枢神经系统症状的菌血症，多见于免疫抑制患者，以及影响健康个体的自限性肠胃炎。极少数情况下，也会出现局灶性感染，如胆囊炎。我们在此报告一例82岁女性由单核细胞增生李斯特菌引起的急性胆囊炎病例。由于治疗成功（胆囊切除术和抗菌治疗，阿莫西林加克拉维酸），患者很快康复。本病例报告为回顾目前关于单核细胞增生李斯特菌与胆囊炎关联的文献提供了契机。
