[桫椤化学成分的研究]

[Study on the chemical constituents from Cyathea spinulosa].

作者信息

Jiang Jian-Shuang, Zhan Zhi-Lai, Feng Zi-Ming, Yang Ya-Nan, Zhang Pei-Cheng

机构信息

State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China.

出版信息

Zhong Yao Cai. 2012 Apr;35(4):568-70.

PMID:23019903

Abstract

OBJECTIVE

To study the chemical constituents from Cyathea spinulosa.

METHODS

Compounds were isolated by chromatographic techniques. Their structures were elucidated by spectral methods.

RESULTS

Eight compounds were isolated from the ethanol extract of Cyathea spinulosa and identified as stigmast-4-ene-3,6-dione (1), stigmast-3,6-dione (2), ergosterol (3), protocatechuic aldehyde (4), 1-O-beta-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl) amido]-4,8- octadecadiene-1,3-diol (5), (2S,3S, 4R)-2-[(2'R) -2'-hydroxytetracosanoylamino]-1,3,4-octadecanetriol (6), beta-sitosterol (7), daucosterol (8).

CONCLUSION

Compounds 1-6 are isolated from this plant for the first time.

摘要

目的

研究刺桫椤的化学成分。

方法

采用色谱技术分离化合物，通过光谱方法鉴定其结构。

结果

从刺桫椤乙醇提取物中分离得到8个化合物，分别鉴定为豆甾-4-烯-3,6-二酮（1）、豆甾-3,6-二酮（2）、麦角甾醇（3）、原儿茶醛（4）、1-O-β-D-吡喃葡萄糖基-(2S,3R,4E,8Z)-2-[(2-羟基十八烷酰基)氨基]-4,8-十八碳二烯-1,3-二醇（5）、(2S,3S,4R)-2-[(2'R)-2'-羟基二十四烷酰氨基]-1,3,4-十八烷三醇（6）、β-谷甾醇（7）、胡萝卜苷（8）。