Benedetto N, Perrini P, Scollato A, Buccoliero A M, Di Lorenzo N
Neurosurgical Department, University of Florence, Firenze, Italy.
Acta Neurochir (Wien). 2007 Aug;149(8):799-803; discussion 803. doi: 10.1007/s00701-007-1239-5. Epub 2007 Aug 1.
Tumour-to-tumour metastasis is a rare pathological entity. Meningioma is the most common intracranial tumour to host metastases, the majority of which arise from breast and lung cancers. We present the first report of a colonic cancer metastasis within an intracranial meningioma.A 76-year-old woman presented with a one month history of partial seizures. Her medical history included resection of an adenocarcinoma of the descending colon followed by adjuvant chemotherapy 1 year before our evaluation. Magnetic resonance imaging revealed a homogeneously enhancing lesion in the right frontal convexity.A well capsulated tumour attached to the frontal dura was surgically removed. The pathological examination demonstrated a mixture of fibrous meningioma and colloid adenocarcinoma. Possible explanations for the development of a cohesive chimeric mass of composite pathology are investigated.
肿瘤-to-肿瘤转移是一种罕见的病理实体。脑膜瘤是最常见的发生转移的颅内肿瘤，其中大多数转移瘤起源于乳腺癌和肺癌。我们报告了首例颅内脑膜瘤内发生结肠癌转移的病例。一名76岁女性，有1个月的部分性癫痫发作病史。她的病史包括在我们评估前1年降结肠癌切除术后接受辅助化疗。磁共振成像显示右额部凸面有一个均匀强化的病变。手术切除了一个附着于额部硬脑膜的包膜完整的肿瘤。病理检查显示为纤维性脑膜瘤和黏液腺癌的混合。对这种具有复合病理的紧密嵌合性肿块的形成原因进行了研究。
