阿尔茨海默病的病毒假说。缺乏针对慢病毒的抗体。
The viral hypothesis of Alzheimer's disease. Absence of antibodies to lentiviruses.
作者信息
Friedland R P, May C, Dahlberg J
机构信息
Section on Brain Aging and Dementia, National Institute on Aging, National Institutes of Health, Bethesda, MD 20891.
出版信息
Arch Neurol. 1990 Feb;47(2):177-8. doi: 10.1001/archneur.1990.00530020083019.
To evaluate the possible role of lentiviruses in Alzheimer's disease we searched for cross-reactive antibodies to human immunodeficiency virus type 1, caprine arthritis encephalitis virus, and equine infectious anemia virus in Alzheimer's disease, Down's syndrome, and related dementing illnesses in serum samples and cerebrospinal fluid samples and in healthy age-matched control subjects. No cross-reactive antibodies were detected.
为评估慢病毒在阿尔茨海默病中的潜在作用，我们在阿尔茨海默病、唐氏综合征及相关痴呆症患者的血清样本、脑脊液样本以及年龄匹配的健康对照者中，寻找针对1型人类免疫缺陷病毒、山羊关节炎脑炎病毒和马传染性贫血病毒的交叉反应性抗体。未检测到交叉反应性抗体。
Zotero 插件