Turgeon P W, Nauheim R C, Roat M I, Stopak S S, Thoft R A
Eye and Ear Institute, University of Pittsburgh, PA 15213.
Arch Ophthalmol. 1990 Feb;108(2):233-6. doi: 10.1001/archopht.1990.01070040085036.
Thirteen patients with ocular surface failure were treated by keratoepithelioplasty using allografts of corneal limbal epithelial cells from donor eyes. The ocular surface was stabilized with long-term healing of persistent epithelial defects in five of eight eyes followed up for 4 to 19 months. The procedure was performed on an additional 5 patients with superficial keratopathies. Three of those five procedures resulted in a stable and clear optical surface. These results suggest that epithelial transplantation may be a useful option in the care of chronic ocular surface failure unresponsive to conventional medical management.
13例眼表衰竭患者接受了角膜缘上皮细胞同种异体移植的角膜上皮成形术治疗。在随访4至19个月的8只眼中,有5只眼的眼表得到稳定,持续性上皮缺损长期愈合。另外5例浅层角膜病变患者也接受了该手术。这5例手术中有3例获得了稳定且清晰的光学表面。这些结果表明,上皮移植可能是治疗对传统药物治疗无反应的慢性眼表衰竭的一种有用方法。