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温水灌肠在镇静状态下结肠镜检查中并不会减少镇静药物的使用量。

Warm water infusion during sedated colonoscopy does not decrease amount of sedation medication used.

机构信息

Division of Gastroenterology, Oregon Health & Science University, Portland, Oregon 97239, USA.

出版信息

Gastrointest Endosc. 2012 Dec;76(6):1182-7. doi: 10.1016/j.gie.2012.08.002. Epub 2012 Sep 26.

DOI:10.1016/j.gie.2012.08.002
PMID:23021168
Abstract

BACKGROUND

Water infusion versus air insufflation during colonoscope insertion has been suggested to reduce patient discomfort and decrease sedation medication requirements. Warm water is thought to further facilitate colonoscopy perhaps by decreasing colon spasm.

OBJECTIVE

To compare the utility of warm (35°-38°C) versus cool (20°-23°C) water infused during colonoscopic insertion by measuring patient sedation medication use and discomfort scores between the warm and cool water groups.

DESIGN

Randomized, controlled, double-blinded study.

SETTING

Outpatient endoscopy unit at an academic medical center.

PATIENTS

A total of 175 adults.

INTERVENTION

Elective outpatient sedated screening colonoscopies.

MAIN OUTCOME MEASUREMENTS

Sedation medication used, pain scores, cecal intubation rate, endoscopy times, satisfaction scores, and patient willingness to repeat procedures.

RESULTS

There was no significant difference in sedation medication requirement during colonoscopy with the use of warm or cool water (fentanyl 83.6 ± 29.0 μg vs 87.6 ± 39.6 μg; P = .45; midazolam 3.3 ± 1.2 mg vs 3.3 ± 1.3 mg; P = .91). There was no significant difference in patient pain scores or satisfaction scores. Cecal intubation rates (100%) were similar. There was no significant difference in cecal intubation times (6 minutes 40 seconds ± 4 minutes 9 seconds vs 7 minutes 49 seconds ± 4 minutes 0 seconds; P = .06) between the warm and cool water groups. All patients were willing to repeat the colonoscopy by using the same method in both groups.

LIMITATIONS

Limited generalizability to patients undergoing screening sedated colonoscopies with good to excellent bowel preparation.

CONCLUSION

Water does not need to be warmed before infusion in patients undergoing sedated colonoscopies.

摘要

背景

在结肠镜检查插入期间,建议使用注水法而非注气法,以减轻患者不适并减少镇静药物的需求。温水被认为可以通过减少结肠痉挛进一步促进结肠镜检查。

目的

通过测量两组患者的镇静药物使用量和不适评分,比较在结肠镜检查插入期间使用温水(35°C-38°C)与冷水(20°C-23°C)的效果。

设计

随机、对照、双盲研究。

地点

学术医疗中心的门诊内镜室。

患者

共 175 名成年人。

干预

择期门诊镇静筛查结肠镜检查。

主要观察指标

镇静药物使用量、疼痛评分、盲肠插管率、内镜检查时间、满意度评分和患者重复程序的意愿。

结果

使用温水或冷水进行结肠镜检查时,镇静药物的需求没有显著差异(芬太尼 83.6±29.0μg 与 87.6±39.6μg;P=.45;咪达唑仑 3.3±1.2mg 与 3.3±1.3mg;P=.91)。患者的疼痛评分和满意度评分没有显著差异。盲肠插管率(100%)相似。两组间盲肠插管时间(6 分 40 秒±4 分 9 秒与 7 分 49 秒±4 分 0 秒;P=.06)无显著差异。所有患者都愿意在两组中重复使用相同的方法进行结肠镜检查。

局限性

对接受镇静筛查结肠镜检查且肠道准备良好至优秀的患者的推广有限。

结论

在接受镇静结肠镜检查的患者中,输注前不需要将水加热。

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