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对功能性鼻内镜鼻窦手术治疗药物治疗无效的成人慢性鼻-鼻窦炎疗效的回顾性分析。

Retrospective analysis of the effectiveness of functional endoscopic sinus surgery in the treatment of adult chronic rhinisinusitis refractory to medical treatment.

作者信息

Shivakumar T, Sambandan A P

机构信息

Department of ENT, Mahathma Gandhi Medical College and Research Institute, Pillaiyarkuppam, Puducherry, 607402 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2011 Oct;63(4):321-4. doi: 10.1007/s12070-011-0238-2. Epub 2011 Apr 11.

Abstract

Chronic rhinosinusitis (CRS) is a common disease that restricts the quality of life of millions of involved patients. The aim of the study was to evaluate how functional endoscopic sinus surgery (FESS) modifies patients symptom profile and to also confirm that FESS is the modality of treatment in patients with refractory CRS. The study was retrospective analysis. 105 patients with symptoms of CRS were included in the study (between August 2006 to July 2009). Patients were assessed for CRS symptoms preoperatively and postoperatively using grading symptoms. Statistical analysis using Chi square test. Leading symptom of CRS was nasal obstruction followed by headache. Furthermore patients reported of anosmia, facial pressure, postnasal drip, purulent nasal discharge, halitosis, dental pain, cough, earache. None of the patients had fever as their complaint. After a postoperative followup of 6 months there was improvement in the symptoms. All minor symptoms had 100% improvement. Nasal obstruction responded best, next followed by (all symptoms P value <0.001). An overall improvement of 86.66% was recorded. The restriction of quality of life in patients with CRS is mainly caused by these symptoms, which can be improved in excellent fashion by FESS in majority of the patients.

摘要

慢性鼻-鼻窦炎(CRS)是一种常见疾病,限制了数百万受累患者的生活质量。本研究的目的是评估功能性鼻内镜鼻窦手术(FESS)如何改变患者的症状表现,并证实FESS是难治性CRS患者的治疗方式。本研究为回顾性分析。研究纳入了105例有CRS症状的患者(2006年8月至2009年7月期间)。术前和术后使用症状分级对患者的CRS症状进行评估。采用卡方检验进行统计分析。CRS的主要症状是鼻塞,其次是头痛。此外,患者还报告有嗅觉减退、面部压迫感、鼻后滴漏、脓性鼻涕、口臭、牙痛、咳嗽、耳痛。没有患者以发热为诉求。术后随访6个月后症状有所改善。所有轻微症状均有100%的改善。鼻塞的改善最为明显,其次是其他症状(所有症状P值<0.001)。总体改善率为86.66%。CRS患者生活质量的受限主要由这些症状引起,在大多数患者中,FESS可以显著改善这些症状。

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