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肾移植中广泛性气肿性肾盂肾炎的保守治疗:病例报告及文献复习

Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature.

作者信息

Alexander S, Varughese S, David V G, Kodgire S V, Mukha R P, Kekre N S, Tamilarasi V, Jacob C K, John G T

机构信息

Department of Nephrology, Christian Medical College, Vellore, India.

出版信息

Transpl Infect Dis. 2012 Dec;14(6):E150-5. doi: 10.1111/tid.12016. Epub 2012 Oct 1.

Abstract

Emphysematous pyelonephritis (EPN) is a rare occurrence in renal allografts. An aggressive approach resulting in transplant nephrectomy is viewed as the standard of care. Over the recent years, treatment with percutaneous drainage (PCD) of the renal and perinephric collections and appropriate antibiotics has been reported with good success in lesser grades of this infection. Only 4 cases of extensive EPN disease with Escherichia coli, treated with conservative management, are reported in the English-language literature. We present a case of severe EPN caused by Klebsiella pneumoniae, successfully managed with early PCD, and propose a step-up strategy aimed toward graft preservation.

摘要

气肿性肾盂肾炎(EPN)在肾移植中较为罕见。采取积极措施导致移植肾切除被视为标准治疗方法。近年来,有报道称,对于病情较轻的此类感染,采用经皮引流(PCD)处理肾脏及肾周积液并使用适当抗生素进行治疗取得了良好效果。英文文献中仅报道了4例采用保守治疗的由大肠杆菌引起的广泛性EPN病例。我们报告1例由肺炎克雷伯菌引起的严重EPN病例,通过早期PCD成功治疗,并提出一种旨在保留移植肾的逐步升级策略。

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