具有酶活性的生物-无机原始细胞内的人工细胞骨架结构。
Artificial cytoskeletal structures within enzymatically active bio-inorganic protocells.
机构信息
Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol, UK.
出版信息
Small. 2013 Feb 11;9(3):357-62. doi: 10.1002/smll.201201539. Epub 2012 Oct 2.
PMID:23027575
Abstract
The fabrication of enzymatically active, semi-permeable bio-inorganic protocells capable of self-assembling a cytoskeletal-like interior and undergoing small-molecule dephosphorylation reactions is described. Reversible disassembly of an amino acid-derived supramolecular hydrogel within the internalized reaction space is used to tune the enzymatic activity of the nanoparticle-bounded inorganic compartments.
摘要
本文描述了具有酶活性和半透性的生物-无机原细胞的制备，这种原细胞能够自组装类似细胞骨架的内部结构，并进行小分子去磷酸化反应。在内部反应空间内，通过可逆解组装氨基酸衍生的超分子水凝胶来调节纳米颗粒结合的无机隔室的酶活性。
Zotero 插件