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2
Crystallization and preliminary X-ray studies of the C-terminal domain of Mycobacterium tuberculosis LexA.结核分枝杆菌LexA C末端结构域的结晶及初步X射线研究
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1093-5. doi: 10.1107/S174430911003068X. Epub 2010 Aug 28.
3
Crystallization and preliminary X-ray studies of a galactose-specific lectin from the seeds of bitter gourd (Momordica charantia).苦瓜(Momordica charantia)种子中一种半乳糖特异性凝集素的结晶及X射线初步研究。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1037-40. doi: 10.1107/S174430911002659X. Epub 2010 Aug 26.
4
M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations.结核分枝杆菌泛酸激酶:双重底物特异性和配体位置的异常变化。
J Mol Biol. 2010 Jul 9;400(2):171-85. doi: 10.1016/j.jmb.2010.04.064. Epub 2010 May 6.
5
Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base.MutT 蛋白在识别具有诱变 8-氧鸟嘌呤碱基的核苷酸中的结构和动态特征。
J Biol Chem. 2010 Jan 1;285(1):444-52. doi: 10.1074/jbc.M109.066373. Epub 2009 Oct 28.
6
A distinct physiological role of MutY in mutation prevention in mycobacteria.MutY 在分枝杆菌突变预防中的独特生理作用。
Microbiology (Reading). 2010 Jan;156(Pt 1):88-93. doi: 10.1099/mic.0.033621-0. Epub 2009 Sep 24.
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Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability.结核分枝杆菌RuvA的晶体学与建模研究:RuvB结合结构域的额外作用及种间变异性
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Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources.分枝杆菌尿嘧啶-DNA糖基化酶的结构及相互作用的独特特征:结核分枝杆菌酶复合物的结构与其他来源酶复合物的比较
Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):551-60. doi: 10.1107/S090744490800512X. Epub 2008 Apr 19.
9
The histidine phosphatase superfamily: structure and function.组氨酸磷酸酶超家族:结构与功能
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Structural studies on the second Mycobacterium smegmatis Dps: invariant and variable features of structure, assembly and function.耻垢分枝杆菌第二种铁结合蛋白的结构研究:结构、组装及功能的不变和可变特征
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耻垢分枝杆菌中MutT1(MSMEG_2390)的结晶及初步X射线研究。

Crystallization and preliminary X-ray studies of MutT1 (MSMEG_2390) from Mycobacterium smegmatis.

作者信息

Arif S M, Patil A G, Varshney U, Vijayan M

机构信息

Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.

出版信息

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1214-6. doi: 10.1107/S1744309112035804. Epub 2012 Sep 26.

DOI:10.1107/S1744309112035804
PMID:23027750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3497982/
Abstract

MutT1 (MSMEG_2390) from Mycobacterium smegmatis has been crystallized and the crystals have been characterized using X-ray diffraction. The crystals belonged to space group P2(1)2(1)2(1). The Matthews coefficient suggested the possibility of one protein molecule in the asymmetric unit of the orthorhombic unit cell. Solution of the structure using the known three-dimensional structure of a bacterial MutT1 is anticipated.

摘要

耻垢分枝杆菌的MutT1(MSMEG_2390)已被结晶,并且使用X射线衍射对晶体进行了表征。晶体属于空间群P2(1)2(1)2(1)。马修斯系数表明在正交晶胞的不对称单元中可能存在一个蛋白质分子。预计将利用细菌MutT1的已知三维结构来解析该结构。