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一例罕见的致命性百草枯意外中毒病例。

An unusual case of fatal accidental paraquat poisoning.

作者信息

Fernando R, Harendra De Silva D G, Amarasena T S

机构信息

Department of Forensic Medicine, Faculty of Medicine, University of Colombo.

出版信息

Forensic Sci Int. 1990 Jan;44(1):23-6. doi: 10.1016/0379-0738(90)90162-r.

DOI:10.1016/0379-0738(90)90162-r
PMID:2303205
Abstract

Paraquat, a useful contact herbicide is now used in over 130 countries of the world, including Sri Lanka. The number of cases of accidental poisoning reported with paraquat is small, relative to instances of suicide. When a clear history is not available, accidental paraquat poisoning is sometimes difficult to diagnose. A 9-year-old boy was admitted to a peripheral hospital with a history of diarrhoea and vomiting. He later developed abdominal pain, subcutaneous emphysema and difficulty in breathing. Following transfer to a district hospital and then to a teaching hospital, poisoning with paraquat was suspected only on day 11 of the illness. On persistent questioning, on day 13 of the illness the child remembered that the day prior to the onset of illness, on his way from a shop, he felt thirsty and having found an empty bottle of Gramoxone (paraquat) on the wayside he used it to drink water from a water tank. The child died on day 17 and the histology of the lung showed typical changes of paraquat poisoning. This tragic episode emphasises the need for proper disposal of empty containers of all poisonous substances.

摘要

百草枯,一种常用的触杀型除草剂,目前在包括斯里兰卡在内的世界130多个国家使用。与自杀案例相比,百草枯意外中毒的报告病例数量较少。当没有明确的病史时,意外百草枯中毒有时难以诊断。一名9岁男孩因腹泻和呕吐病史入住一家基层医院。他后来出现腹痛、皮下气肿和呼吸困难。转至地区医院,然后又转至教学医院后,直到患病第11天才怀疑是百草枯中毒。经过持续询问,在患病第13天,孩子想起在发病前一天,他从商店回来的路上感到口渴,在路边发现一个空的克无踪(百草枯)瓶子,就用它从水箱里喝水。孩子于第17天死亡,肺部组织学检查显示出百草枯中毒的典型变化。这一悲惨事件强调了妥善处理所有有毒物质空容器的必要性。

相似文献

1
An unusual case of fatal accidental paraquat poisoning.一例罕见的致命性百草枯意外中毒病例。
Forensic Sci Int. 1990 Jan;44(1):23-6. doi: 10.1016/0379-0738(90)90162-r.
2
[Fatal voluntary poisoning by parenteral paraquat].[经胃肠外途径摄入百草枯导致的致命性蓄意中毒]
Schweiz Med Wochenschr. 1991 Sep 7;121(36):1293-7.
3
Accidental paraquat induced hypersalivation: a case report.意外摄入百草枯导致唾液分泌过多:一例报告。
Daru. 2019 Dec;27(2):885-888. doi: 10.1007/s40199-019-00298-9. Epub 2019 Sep 5.
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Paraquat poisoning: Acute lung injury - a missed diagnosis.百草枯中毒:急性肺损伤——漏诊病例
S Afr Med J. 2017 Apr 25;107(5):399-401. doi: 10.7196/SAMJ.2017.v107i5.12306.
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Paraquat poisoning in southern Mexico: a report of 25 cases.
Arch Environ Health. 1993 Mar-Apr;48(2):78-80. doi: 10.1080/00039896.1993.9938398.
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Paraquat induced acute kidney injury and lung fibrosis: a case report from Bangladesh.百草枯诱发急性肾损伤和肺纤维化:来自孟加拉国的一例报告。
BMC Res Notes. 2018 May 30;11(1):344. doi: 10.1186/s13104-018-3425-3.
7
[Toxicologic identification, pathogenesis and time dependence of changes in acute gramoxone (Paraquat) poisoning. II. Pathogenesis and time dependence of organ changes].
Cesk Patol. 1973 Nov;9(4):Suppl:49-58.
8
A Deadly Herbicide 'Paraquat Poisoning' and Miserable Death of a 19 Years Boy.一种致命除草剂“百草枯中毒”和一个 19 岁男孩的悲惨死亡。
Mymensingh Med J. 2022 Jul;31(3):869-871.
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Brain damage due to paraquat poisoning: a fatal case with neuropathological examination of the brain.百草枯中毒所致脑损伤:一例经脑病理检查的致死病例
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[Fatal poisoning with paraquat: report of a new case].[百草枯致死性中毒:1例新病例报告]
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引用本文的文献

1
A Forensic Case of Suicide Ingestion of Paraquat Herbicide: New Histological Insights and Revision of the Literature.一起百草枯除草剂自杀摄入的法医案例:新的组织学见解和文献复习。
Am J Forensic Med Pathol. 2024 Mar 1;45(1):81-87. doi: 10.1097/PAF.0000000000000878.
2
Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand.泰国农业地区孕妇和新生儿接触百草枯情况。
Int J Environ Res Public Health. 2018 Jun 3;15(6):1163. doi: 10.3390/ijerph15061163.