Department of Medicine, University of Washington, Harborview Medical Center, Seattle, WA, USA.
Stroke. 2013 Jan;44(1):263-9. doi: 10.1161/STROKEAHA.112.653618. Epub 2012 Oct 2.
The Nobel laureate Max Delbrück often said that it is the crossover between disciplines where advances are possible in science. This certainly has been true for our understanding of the vascular biology of the central nervous system in the setting of ischemic stroke. The ability to cross the boundaries of hemostasis, neurology, hematology, and neuroscience has facilitated our research direction to define the relation of the microvasculature to neuron function. Work begun with the clinical scientific exploration of the contributions of arterial thrombosis to the acute injury processes initiated by focal cerebral ischemia has led to an increased understanding of the effects of ischemia on microvessel integrity.
诺贝尔奖得主马克斯·德尔布吕克（Max Delbrück）常说，学科交叉是科学取得进展的地方。在我们对缺血性中风情况下中枢神经系统血管生物学的理解方面，这无疑是正确的。止血、神经学、血液学和神经科学之间的交叉能力促进了我们的研究方向，以确定微血管与神经元功能的关系。从临床科学角度探索动脉血栓形成对局灶性脑缺血引发的急性损伤过程的贡献开始的工作，使我们对缺血对微血管完整性的影响有了更深入的了解。
