环鸟苷酸与青蛙光感受器盘膜的通透性
Cyclic GMP and the permeability of the disks of the frog photoreceptors.
作者信息
Caretta A, Cavaggioni A, Sorbi R T
出版信息
J Physiol. 1979 Oct;295:171-8. doi: 10.1113/jphysiol.1979.sp012959.
Abstract
- The diffusion of sodium, potassium and rubidium (not chloride) ions across the disk membrane is increased by cyclic guanosine monophosphate (cyclic GMP). 2. The increase is greater for sodium than for rubidium in the 0.01-0.1 mM concentration range. 3. Cyclic adenosine monophosphate (cyclic AMP) is less efficient than cyclic GMP; GMP and guanosine triphosphate are without effect. 4. The effect is present with either 1.8 mM calcium ions or 4 mM-EGTA in the perfusion fluid. 5. The presence of the cyclic GMP phosphodiesterase on the disk membranes is not needed for this effect. 6. The effect is present in both unbleached and fully bleached membranes.
摘要
- 环磷酸鸟苷（环GMP）可增加钠、钾和铷（而非氯）离子跨盘膜的扩散。2. 在0.01 - 0.1 mM浓度范围内，钠的增加幅度大于铷。3. 环磷酸腺苷（环AMP）的效率低于环GMP；GMP和三磷酸鸟苷无作用。4. 灌注液中存在1.8 mM钙离子或4 mM乙二醇双四乙酸（EGTA）时该效应依然存在。5. 此效应不需要盘膜上存在环GMP磷酸二酯酶。6. 未漂白和完全漂白的膜中均存在该效应。
相似文献
1
Cyclic GMP and the permeability of the disks of the frog photoreceptors.环鸟苷酸与青蛙光感受器盘膜的通透性
J Physiol. 1979 Oct;295:171-8. doi: 10.1113/jphysiol.1979.sp012959.
2
Effect of cGMP and cations on the permeability of cattle retinal disks.环磷酸鸟苷（cGMP）和阳离子对牛视网膜盘通透性的影响。
Eur J Biochem. 1985 May 2;148(3):599-606. doi: 10.1111/j.1432-1033.1985.tb08882.x.
3
[Mechanism of vertebrate photoreceptor excitation: possible role of cyclic nucleotides].[脊椎动物光感受器兴奋机制：环核苷酸的可能作用]
Dokl Akad Nauk SSSR. 1977;237(3):739-42.
4
Guanosine 3',5'-cyclic monophosphate and the in vitro physiology of frog photoreceptor membranes.3',5'-环磷酸鸟苷与蛙类光感受器膜的体外生理学
J Gen Physiol. 1977 May;69(5):667-79. doi: 10.1085/jgp.69.5.667.
5
Amplitude, kinetics, and reversibility of a light-induced decrease in guanosine 3',5'-cyclic monophosphate in frog photoreceptor membranes.青蛙光感受器膜中光诱导的3',5'-环磷酸鸟苷减少的幅度、动力学及可逆性。
J Gen Physiol. 1979 May;73(5):629-53. doi: 10.1085/jgp.73.5.629.
6
Activation of photoreceptor disk membrane phosphodiesterase by light and ATP.光和ATP对光感受器盘膜磷酸二酯酶的激活作用。
Adv Cyclic Nucleotide Res. 1975;5:213-40.
7
[Action of cyclic nucleotides on the cytoplasmic membrane conductance of the rod outer segment in the retina].[环核苷酸对视网膜视杆外段细胞质膜电导的作用]
Dokl Akad Nauk SSSR. 1982;262(5):1269-72.
8
Efflux of potassium from isolated rod outer segments: a photic effect.钾离子从离体视杆细胞外段的流出：一种光效应。
J Physiol. 1973 Aug;232(3):609-20. doi: 10.1113/jphysiol.1973.sp010288.
9
Cyclic guanosine 3',5'-monophosphate regulates the calcium current in single cells from frog ventricle.环磷酸鸟苷调节蛙心室单细胞中的钙电流。
J Physiol. 1987 Jun;387:453-72. doi: 10.1113/jphysiol.1987.sp016584.
10
Calcium and cyclic GMP regulation of light-sensitive protein phosphorylation in frog photoreceptor membranes.青蛙光感受器膜中钙和环鸟苷酸对光敏感蛋白磷酸化的调节
J Gen Physiol. 1982 Apr;79(4):633-55. doi: 10.1085/jgp.79.4.633.
引用本文的文献
1
How vision begins: an odyssey.视觉的起源：一段探索之旅。
Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9855-62. doi: 10.1073/pnas.0708405105. Epub 2008 Jul 16.
2
Cyclic GMP releases calcium from disc membranes of vertebrate photoreceptors.环磷酸鸟苷从脊椎动物光感受器的盘膜中释放钙。
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3964-8. doi: 10.1073/pnas.78.6.3964.
3
Incorporation of a retinal rod cGMP-dependent conductance into planar bilayers.将视网膜视杆细胞环鸟苷酸依赖性电导整合到平面双层膜中。
Proc Natl Acad Sci U S A. 1987 Feb;84(3):724-8. doi: 10.1073/pnas.84.3.724.
4
Control of the light-regulated current in rod photoreceptors by cyclic GMP, calcium, and l-cis-diltiazem.环磷酸鸟苷、钙和左旋顺式地尔硫䓬对视杆光感受器中光调节电流的控制
Proc Natl Acad Sci U S A. 1986 Feb;83(4):1163-7. doi: 10.1073/pnas.83.4.1163.
5
The opsin family of proteins.视蛋白家族蛋白质。
Biochem J. 1986 Sep 15;238(3):625-42. doi: 10.1042/bj2380625.
6
Visualization of cyclic nucleotide binding sites in the vertebrate retina by fluorescence microscopy.通过荧光显微镜观察脊椎动物视网膜中环状核苷酸结合位点
J Cell Biol. 1989 Apr;108(4):1517-22. doi: 10.1083/jcb.108.4.1517.
7
Opsin exhibits cGMP-activated single-channel activity.视蛋白表现出cGMP激活的单通道活性。
Proc Natl Acad Sci U S A. 1988 Dec;85(24):9806-10. doi: 10.1073/pnas.85.24.9806.
8
Guanosine 3',5'-cyclic monophosphate-activated conductance studied in a truncated rod outer segment of the toad.在蟾蜍截短的视杆外段中研究的3',5'-环磷酸鸟苷激活的电导。
J Physiol. 1988 Jan;395:731-53. doi: 10.1113/jphysiol.1988.sp016943.
9
Diltiazem at high concentration increases the ionic permeability of biological membranes.高浓度地尔硫䓬可增加生物膜的离子通透性。
J Membr Biol. 1991 Jun;122(3):203-13. doi: 10.1007/BF01871421.
本文引用的文献
1
Efflux of potassium from isolated rod outer segments: a photic effect.钾离子从离体视杆细胞外段的流出：一种光效应。
J Physiol. 1973 Aug;232(3):609-20. doi: 10.1113/jphysiol.1973.sp010288.
2
Light activation of phosphodiesterase activity in retinal rod outer segments.视网膜视杆细胞外段中磷酸二酯酶活性的光激活。
Biochim Biophys Acta. 1974 Jun 28;347(3):491-3. doi: 10.1016/0005-2728(74)90086-3.
3
Light-regulated guanosine 3',5'-monophosphate phosphodiesterase of bovine retina.牛视网膜的光调节鸟苷 3',5'-单磷酸磷酸二酯酶
Nature. 1974 Mar 1;248(5443):57-8. doi: 10.1038/248057a0.
4
Effect of strong illumination on the ion efflux from the isolated discs of frog photoreceptors.强光对离体青蛙光感受器盘离子外流的影响。
Biochim Biophys Acta. 1975 Jul 18;394(4):577-85. doi: 10.1016/0005-2736(75)90143-1.
5
On the metabolism of the rod outer segments.关于视杆细胞外段的代谢
J Physiol. 1976 Jun;257(3):687-97. doi: 10.1113/jphysiol.1976.sp011392.
6
Light-activated hydrolysis of GTP and cyclic GMP in the rod outer segments.视杆细胞外段中GTP和环鸟苷酸的光激活水解作用。
J Physiol. 1978 Jun;279:55-69. doi: 10.1113/jphysiol.1978.sp012330.
7
A light-activated GTPase in vertebrate photoreceptors: regulation of light-activated cyclic GMP phosphodiesterase.脊椎动物光感受器中的一种光激活型鸟苷三磷酸酶：光激活型环鸟苷酸磷酸二酯酶的调节
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4238-42. doi: 10.1073/pnas.74.10.4238.
8
Guanosine 3',5'-cyclic monophosphate and the in vitro physiology of frog photoreceptor membranes.3',5'-环磷酸鸟苷与蛙类光感受器膜的体外生理学
J Gen Physiol. 1977 May;69(5):667-79. doi: 10.1085/jgp.69.5.667.
9
Biochemical correlates of adaptation processes in isolated frog photoreceptor membranes.离体青蛙光感受器膜中适应过程的生化关联
J Gen Physiol. 1976 Jul;68(1):1-11. doi: 10.1085/jgp.68.1.1.
10
Light-sensitive swelling of isolated frog rod outer segments as an in vitro assay for visual transduction and dark adaptation.离体青蛙视杆细胞外段的光敏肿胀作为视觉转导和暗适应的体外测定方法。
J Gen Physiol. 1975 Oct;66(4):407-25. doi: 10.1085/jgp.66.4.407.
Zotero 插件