Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands.
J Am Dent Assoc. 2012 Oct;143(10 Suppl):12S-8S. doi: 10.14219/jada.archive.2012.0338.
Diagnostics that involve the use of oral fluids have become increasingly available commercially in recent years and are of particular interest because of their relative ease of use, low cost and noninvasive collection of oral fluid for testing.
The authors discuss the use of salivary diagnostics for virus detection with an emphasis on rapid detection of infection by using point-of-care devices. In particular, they review salivary diagnostics for human immunodeficiency virus, hepatitis C virus and human papillomavirus. Oral mucosal transudate contains secretory immunoglobulin (Ig) A, as well as IgM and IgG, which makes it a good source for immunodiagnostic-based devices.
Because patients often visit a dentist more regularly than they do a physician, there is increased discussion in the dental community regarding the need for practitioners to be aware of salivary diagnostics and to be willing and able to administer these tests to their patients.
近年来，涉及口腔液的诊断方法在商业上越来越普及，由于其使用相对简便、成本低且可无创采集口腔液进行检测，因此受到特别关注。
作者讨论了唾液诊断在病毒检测中的应用，重点是使用即时检测设备快速检测感染。具体而言，他们综述了唾液诊断在人类免疫缺陷病毒、丙型肝炎病毒和人乳头瘤病毒方面的应用。口腔黏膜渗出液含有分泌型免疫球蛋白（Ig）A 以及 IgM 和 IgG，这使其成为免疫诊断为基础的设备的良好来源。
由于患者看牙医的频率通常高于看医生，因此在牙医群体中越来越多地讨论从业者需要了解唾液诊断，并愿意且能够为其患者进行这些检测。
