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全髋关节置换术后因脱位而翻修的风险取决于手术入路、股骨头大小、性别和主要诊断。对瑞典髋关节置换登记处的 78098 例手术的分析。

The risk of revision due to dislocation after total hip arthroplasty depends on surgical approach, femoral head size, sex, and primary diagnosis. An analysis of 78,098 operations in the Swedish Hip Arthroplasty Register.

机构信息

Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.

出版信息

Acta Orthop. 2012 Oct;83(5):442-8. doi: 10.3109/17453674.2012.733919. Epub 2012 Oct 8.

Abstract

BACKGROUND AND PURPOSE

The effects of patient-related and technical factors on the risk of revision due to dislocation after primary total hip arthroplasty (THA) are only partly understood. We hypothesized that increasing the femoral head size can reduce this risk, that the lateral surgical approach is associated with a lower risk than the posterior and minimally invasive approaches, and that gender and diagnosis influence the risk of revision due to dislocation.

PATIENTS AND METHODS

Data on 78,098 THAs in 61,743 patients performed between 2005 and 2010 were extracted from the Swedish Hip Arthroplasty Register. Inclusion criteria were a head size of 22, 28, 32, or 36 mm, or the use of a dual-mobility cup. The covariates age, sex, primary diagnosis, type of surgical approach, and head size were entered into Cox proportional hazards models in order to calculate the adjusted relative risk (RR) of revision due to dislocation, with 95% confidence intervals (CI).

RESULTS

After a mean follow-up of 2.7 (0-6) years, 399 hips (0.5%) had been revised due to dislocation. The use of 22-mm femoral heads resulted in a higher risk of revision than the use of 28-mm heads (RR = 2.0, CI: 1.2-3.3). Only 1 of 287 dual-mobility cups had been revised due to dislocation. Compared with the direct lateral approach, minimally invasive approaches were associated with a higher risk of revision due to dislocation (RR = 4.2, CI: 2.3-7.7), as were posterior approaches (RR = 1.3, CI: 1.1-1.7). An increased risk of revision due to dislocation was found for the diagnoses femoral neck fracture (RR = 3.9, CI: 3.1-5.0) and osteonecrosis of the femoral head (RR = 3.7, CI: 2.5-5.5), whereas women were at lower risk than men (RR = 0.8, CI: 0.7-1.0). Restriction of the analysis to the first 6 months after the index procedure gave similar risk estimates.

INTERPRETATION

Patients with femoral neck fracture or osteonecrosis of the femoral head are at higher risk of dislocation. Use of the minimally invasive and posterior approaches also increases this risk, and we raise the question of whether patients belonging to risk groups should be operated using lateral approaches. The use of femoral head diameters above 28 mm or of dual-mobility cups reduced this risk in a clinically relevant manner, but this observation was not statistically significant.

摘要

背景与目的

初次全髋关节置换术后因脱位而翻修的风险受患者相关因素和技术因素的影响,但目前仅部分因素得到了阐明。我们假设增大股骨头尺寸可以降低这种风险,外侧手术入路与后外侧和微创入路相比,脱位翻修风险更低,性别和诊断也会影响脱位翻修风险。

患者与方法

我们从瑞典髋关节置换登记处提取了 2005 年至 2010 年间行初次全髋关节置换术的 61743 例患者的 78098 例髋关节数据。纳入标准为股骨头尺寸为 22、28、32 或 36mm,或使用双动杯。将年龄、性别、原发诊断、手术入路类型和股骨头尺寸等协变量纳入 Cox 比例风险模型,以计算脱位翻修的校正相对风险(RR)及其 95%置信区间(CI)。

结果

平均随访 2.7(0-6)年后,399 髋(0.5%)因脱位而翻修。与使用 28mm 股骨头相比,使用 22mm 股骨头的翻修风险更高(RR=2.0,95%CI:1.2-3.3)。仅 1 例双动杯中因脱位而翻修。与直接外侧入路相比,微创入路(RR=4.2,95%CI:2.3-7.7)和后外侧入路(RR=1.3,95%CI:1.1-1.7)与脱位翻修风险更高相关。股骨颈骨折(RR=3.9,95%CI:3.1-5.0)和股骨头缺血性坏死(RR=3.7,95%CI:2.5-5.5)的诊断与脱位翻修风险增加相关,而女性的风险低于男性(RR=0.8,95%CI:0.7-1.0)。将分析限制在索引手术后的前 6 个月,得到了相似的风险估计值。

解释

股骨颈骨折或股骨头缺血性坏死的患者脱位风险更高。微创入路和后外侧入路的使用也会增加这种风险,我们提出了一个问题,即是否应让属于高危人群的患者采用外侧入路进行手术。以临床相关的方式增大股骨头尺寸或使用双动杯可以降低这种风险,但这一观察结果无统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7a4/3488169/fe6d140335c9/ORT-1745-3674-083-442_g001.jpg

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