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犬类杓状软骨肉瘤的成功治疗

Successful management of an arytenoid chondrosarcoma in a dog.

作者信息

Muraro L, Aprea F, White R A S

机构信息

Dick White Referrals Station Farm, London Road, Six Mile Bottom, Newmarket, CB8 0UH.

出版信息

J Small Anim Pract. 2013 Jan;54(1):33-5. doi: 10.1111/j.1748-5827.2012.01287.x. Epub 2012 Oct 8.

Abstract

An eight-year-old Doberman pinscher was presented with a four-week history of inspiratory stridor, dysphonia, inappetence and weight loss. Inspiratory stridor was apparent and became more pronounced during gentle compression of the larynx. Previous investigations, including laryngoscopy, had revealed the presence of a left-sided arytenoid mass. Histological examination of pinch biopsies was not diagnostic. The mass was removed by resection of the arytenoid cartilage through a ventral laryngotomy allowing salvage of the cuneiform process. Histological examination of the laryngeal mass was consistent with a chondrosarcoma, grade I, infiltrating the arytenoid cartilage. Re-examination at 12 months showed complete resolution of the clinical signs and no signs of metastatic disease. To the authors' knowledge this is the first report of successful surgical intervention for laryngeal chondrosarcoma. This case demonstrates that resection via a ventral laryngotomy may be a viable and curative therapeutic option for some sarcomas of the larynx.

摘要

一只八岁的杜宾犬出现吸气性喘鸣、声音嘶哑、食欲不振和体重减轻四周的病史。吸气性喘鸣明显,在轻柔按压喉部时更加明显。先前的检查,包括喉镜检查,发现左侧杓状软骨有肿物。钳取活检的组织学检查未能确诊。通过腹侧喉切开术切除杓状软骨,从而切除肿物,保留了楔状突。喉部肿物的组织学检查结果符合I级软骨肉瘤,浸润杓状软骨。12个月后的复查显示临床症状完全缓解,无转移疾病迹象。据作者所知,这是首例成功手术治疗喉软骨肉瘤的报告。该病例表明,对于一些喉部肉瘤,经腹侧喉切开术切除可能是一种可行的治愈性治疗选择。

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