Kanotra Sohit P, Kanotra Sonika, Paul J, Jamwal Padam S
Department of Otorhinolaryngology, Government Medical College Srinagar, Kashmir, India.
Ear Nose Throat J. 2010 Jan;89(1):E6-E10.
Chondrosarcoma is the most frequently encountered nonepithelial tumor of the larynx. Still, laryngeal chondrosarcoma is a rare disease, accounting for less than 1% of all laryngeal neoplasms; only about 600 cases have been reported in the world literature. The two most common sites of origin are the cricoid cartilage (69% of cases) and the thyroid cartilage (9%); arytenoid cartilage origin has been seen in less than 3% of cases. The diagnosis of laryngeal chondrosarcoma is easy to miss because of its infrequent occurrence, its indolent pattern of growth, and the difficulty in differentiating it histopathologically from chondroma. However, suspicion of arytenoid chondrosarcoma may be raised by a finding of its characteristic appearance as a smooth, hard, mucosa-covered supraglottic mass that is fairly recognizable on indirect laryngoscopy. We report a new case of chondrosarcoma of the arytenoid cartilage in a 47-year-old man, and we discuss the clinical features, diagnosis, and management of this uncommon tumor.
软骨肉瘤是喉最常见的非上皮性肿瘤。然而，喉软骨肉瘤是一种罕见疾病，占所有喉肿瘤的比例不到1%；世界文献中仅报道了约600例。最常见的两个起源部位是环状软骨（69%的病例）和甲状软骨（9%）；杓状软骨起源的病例不到3%。喉软骨肉瘤的诊断容易被漏诊，因为其发病率低、生长缓慢，且在组织病理学上难以与软骨瘤区分。然而，间接喉镜检查时发现杓状软骨肉瘤表现为光滑、坚硬、黏膜覆盖的声门上肿物，特征明显，可引起对其的怀疑。我们报告了一例47岁男性杓状软骨软骨肉瘤的新病例，并讨论了这种罕见肿瘤的临床特征、诊断和治疗。
