Department of Periodontics, Faculty of Dentistry, National University of Singapore, Singapore.
J Evid Based Dent Pract. 2012 Sep;12(3 Suppl):129-42. doi: 10.1016/S1532-3382(12)70025-8.
Can newly introduced graft materials be successfully used in soft tissue augmentation around teeth and dental implants?
An electronic search on the PubMed database for English articles published before March 31, 2012, was performed using the following key words: "root coverage," "soft tissue graft," "periodontal plastic surgery," "subepithelial connective graft (SCTG)," "acellular dermal matrix (ADM)," "guided tissue regeneration based root coverage (GTRC)," "recession defects," "mucogingival defects," "collagen matrix," "living cellular construct (LCC)," "mucograft," and "biologic agents." Literature featuring new soft tissue graft materials, such as ADM, collagen matrix, GTRC, and biologic agents, were included.
Data showed (1) allogeneic grafts were comparable to SCTG in terms of mean complete root coverage (CRC), mean root coverage (RC), and mean amount of keratinized tissue (KT) gain; (2) xenogeneic collagen matrix was as comparable to SCTG in terms of mean amount of KT gain around teeth and dental implants but inferior in achieving RC; (3) GTRC was inferior to SCTG in terms of mean CRC and mean RC; (4) LCC was inferior to free gingival graft in terms of mean amount of KT gain but was superior in esthetics and patient satisfaction; and (5) adjunctive use of biologic agents did not exert a significant effect on mean CRC, mean RC, and mean amount of KT gain.
Although these new materials do not surpass the gold standard (SCTG), they do provide improved patient satisfaction and esthetics, are available in abundance, and lead to reduced postoperative discomfort and surgical time.
新引入的移植物材料能否成功地用于牙齿和牙种植体周围的软组织增量?
在 2012 年 3 月 31 日之前,使用以下关键词在 PubMed 数据库上对英文文章进行电子检索:“根覆盖”、“软组织移植物”、“牙周整形手术”、“上皮下结缔组织移植物(SCTG)”、“脱细胞真皮基质(ADM)”、“基于引导组织再生的根覆盖(GTRC)”、“退缩缺陷”、“黏膜牙龈缺陷”、“胶原基质”、“活细胞构建体(LCC)”、“黏膜移植”和“生物制剂”。纳入了具有新型软组织移植物材料(如 ADM、胶原基质、GTRC 和生物制剂)的文献。
数据显示:(1)同种异体移植物在完全根覆盖(CRC)、根覆盖(RC)和角化组织(KT)获得量的平均方面与 SCTG 相当;(2)异种胶原基质在牙齿和牙种植体周围的 KT 获得量方面与 SCTG 相当,但 RC 效果较差;(3)GTRC 在 CRC 和 RC 的平均方面劣于 SCTG;(4)LCC 在 KT 获得量的平均方面劣于游离龈移植,但在美学和患者满意度方面占优势;(5)生物制剂的辅助应用对 CRC、RC 和 KT 获得量的平均无显著影响。
虽然这些新材料并未超过金标准(SCTG),但它们确实提供了更好的患者满意度和美学效果,且供应充足,导致术后不适和手术时间减少。