• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于退缩覆盖的胶原基质与上皮下结缔组织：一项系统评价。

Collagen Matrix Versus Subepithelial Connective Tissue for Recession Coverage: A Systematic Review.

作者信息

Zangani Alessandro, Gualtieri Miriana, Pardo Alessia, Signoriello Annarita, Faccioni Paolo, Colapinto Gianluca, Goker Funda, Lombardo Giorgio, Del Fabbro Massimo, Albanese Massimo

机构信息

Dentistry and Maxillofacial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Verona, Italy.

Department of Biomedical, Surgical and Dental Sciences, Università Degli Studi di Milano, Milan, Italy.

出版信息

Oral Dis. 2025 Apr;31(4):1092-1106. doi: 10.1111/odi.15203. Epub 2024 Dec 9.

DOI:10.1111/odi.15203
PMID:39652800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12022388/
Abstract

OBJECTIVE

To evaluate the outcome of collagen matrix (CMX) compared with subepithelial connective tissue graft (SCTG) in gingival recession coverage (RC) surgery.

METHODS

Review protocol was registered in PROSPERO. The search was conducted on MEDLINE, Cochrane Library, and Scopus databases. Randomized studies comparing CMX versus. SCTG or CMX versus. covering procedures without any filling material, for class I recession treatment were included. Risk of bias assessment and quantitative analysis were performed.

RESULTS

Of 168 records, 11 randomized clinical trials were included. The meta-analysis revealed no statistically significant difference in terms of %RC (p = 0.37); there was a statistically significant difference in terms of recession reduction (p = 0.02) and keratinized tissue width (p = 0.03) in favor of SCTG cases. CMX showed a statistically significantly better result compared to no grafting, regarding %RC (p = 0.003) and keratinized tissue thickness (p < 0.0001). The duration of the intervention was significantly shorter for CMX than for SCTG (p < 0.0001).

CONCLUSION

CMX can be considered a viable material, especially when a ΔKTt increase and a reduction of intervention duration is needed. The indications for the choice, however, may depend on the individual local condition. PROSPERO Registration: Registration in PROSPERO (International prospective register of systematic reviews): CRD42024555443.

摘要

目的

评估在牙龈退缩覆盖（RC）手术中，胶原蛋白基质（CMX）与上皮下结缔组织移植（SCTG）相比的效果。

方法

检索方案已在PROSPERO中注册。在MEDLINE、Cochrane图书馆和Scopus数据库中进行检索。纳入比较CMX与SCTG或CMX与无任何填充材料的覆盖程序用于I类退缩治疗的随机研究。进行偏倚风险评估和定量分析。

结果

在168条记录中，纳入了11项随机临床试验。荟萃分析显示，在RC百分比方面无统计学显著差异（p = 0.37）；在退缩减少（p = 0.02）和角化组织宽度（p = 0.03）方面存在统计学显著差异，有利于SCTG病例。在RC百分比（p = 0.003）和角化组织厚度（p < 0.0001）方面，与不进行移植相比，CMX显示出统计学上显著更好的结果。CMX的干预持续时间明显短于SCTG（p < 0.0001）。

结论

CMX可被视为一种可行的材料，尤其是在需要增加ΔKTt和缩短干预持续时间时。然而，选择的适应症可能取决于个体局部情况。PROSPERO注册：在PROSPERO（国际系统评价前瞻性注册库）中注册：CRD42024555443。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/7caebb8c44f2/ODI-31-1092-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/f35efbeea672/ODI-31-1092-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/e64d2ced7b98/ODI-31-1092-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/089a16402028/ODI-31-1092-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/9d6dd9bd54d7/ODI-31-1092-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/59e5202613d2/ODI-31-1092-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/c1f8c4c334a5/ODI-31-1092-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/7caebb8c44f2/ODI-31-1092-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/f35efbeea672/ODI-31-1092-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/e64d2ced7b98/ODI-31-1092-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/089a16402028/ODI-31-1092-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/9d6dd9bd54d7/ODI-31-1092-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/59e5202613d2/ODI-31-1092-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/c1f8c4c334a5/ODI-31-1092-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b14/12022388/7caebb8c44f2/ODI-31-1092-g003.jpg

相似文献

1
Collagen Matrix Versus Subepithelial Connective Tissue for Recession Coverage: A Systematic Review.用于退缩覆盖的胶原基质与上皮下结缔组织：一项系统评价。
Oral Dis. 2025 Apr;31(4):1092-1106. doi: 10.1111/odi.15203. Epub 2024 Dec 9.
2
Efficacy of biologics in root coverage and gingival augmentation therapy: An American Academy of Periodontology best evidence systematic review and network meta-analysis.生物制剂在根覆盖和牙龈增量治疗中的疗效：美国牙周病学会最佳证据系统评价和网络荟萃分析。
J Periodontol. 2022 Dec;93(12):1771-1802. doi: 10.1002/JPER.22-0075. Epub 2022 Oct 24.
3
Can subepithelial connective tissue grafts be considered the gold standard procedure in the treatment of Miller Class I and II recession-type defects?上皮下结缔组织移植术能否被视为治疗米勒I类和II类牙龈退缩型缺损的金标准手术？
J Dent. 2008 Sep;36(9):659-71. doi: 10.1016/j.jdent.2008.05.007. Epub 2008 Jun 26.
4
Root coverage procedures for the treatment of localised recession-type defects.用于治疗局限性退缩型缺损的牙根覆盖术。
Cochrane Database Syst Rev. 2009 Apr 15(2):CD007161. doi: 10.1002/14651858.CD007161.pub2.
5
Periodontal soft tissue root coverage procedures: a systematic review from the AAP Regeneration Workshop.牙周软组织根面覆盖手术：来自美国牙周病学会再生研讨会的系统评价
J Periodontol. 2015 Feb;86(2 Suppl):S8-51. doi: 10.1902/jop.2015.130674.
6
Root-coverage procedures for the treatment of localized recession-type defects: a Cochrane systematic review.根覆盖程序治疗局限性退缩型缺损：Cochrane 系统评价。
J Periodontol. 2010 Apr;81(4):452-78. doi: 10.1902/jop.2010.090540.
7
Comparing Connective Tissue Grafts and Collagen Matrix in Modified Coronally Advanced Tunnel Technique for RT1 Gingival Recession: A Randomized Controlled Clinical Trial.在改良冠向推进隧道技术治疗RT1型牙龈退缩中比较结缔组织移植与胶原基质：一项随机对照临床试验
BMC Oral Health. 2025 Jun 3;25(1):893. doi: 10.1186/s12903-025-06259-w.
8
Guided tissue regeneration for periodontal infra-bony defects.牙周骨下袋缺损的引导组织再生术。
Cochrane Database Syst Rev. 2006 Apr 19(2):CD001724. doi: 10.1002/14651858.CD001724.pub2.
9
Long-term stability of gingival margin and periodontal soft-tissue phenotype achieved after mucogingival therapy: A systematic review.黏膜-牙龈治疗后获得的牙龈边缘和牙周软组织表型的长期稳定性：一项系统评价。
J Clin Periodontol. 2024 Feb;51(2):177-195. doi: 10.1111/jcpe.13900. Epub 2023 Nov 14.
10
Xenogeneic collagen matrix for periodontal plastic surgery procedures: a systematic review and meta-analysis.用于牙周整形手术的异种胶原基质：一项系统评价与荟萃分析
J Periodontal Res. 2016 Aug;51(4):438-52. doi: 10.1111/jre.12333. Epub 2015 Nov 7.

本文引用的文献

1
Levels of smoking and outcome measures of root coverage procedures: a systematic review and meta-analysis.吸烟水平与根覆盖手术的结局评估指标：系统评价与荟萃分析。
Oral Maxillofac Surg. 2024 Jun;28(2):485-497. doi: 10.1007/s10006-023-01172-4. Epub 2023 Aug 2.
2
Evaluation of mid-buccal gingival recessions and occlusal interferences.评价颊面中部牙龈退缩和咬合干扰。
J Oral Rehabil. 2023 Oct;50(10):1058-1069. doi: 10.1111/joor.13543. Epub 2023 Jul 3.
3
Tunnel vs. coronally advanced flap in combination with a connective tissue graft for the treatment of multiple gingival recessions: a multi-center randomized clinical trial.
隧道瓣与冠向瓣推进术联合结缔组织移植治疗多个牙龈退缩：一项多中心随机临床试验。
Clin Oral Investig. 2023 Jul;27(7):3627-3638. doi: 10.1007/s00784-023-04975-7. Epub 2023 Mar 29.
4
Gingival phenotype changes after different periodontal plastic surgical techniques: a single-masked randomized controlled clinical trial.不同牙周整形手术技术后的牙龈表型变化：一项单盲随机对照临床试验。
Clin Oral Investig. 2023 Jul;27(7):3423-3435. doi: 10.1007/s00784-023-04944-0. Epub 2023 Mar 17.
5
Soft-Tissue Augmentation around Dental Implants with a Connective Tissue Graft (CTG) and Xenogeneic Collagen Matrix (CMX)-5-Year Follow-Up.使用结缔组织移植（CTG）和异种胶原基质（CMX）对牙种植体周围软组织进行增量术——5年随访
J Clin Med. 2023 Jan 24;12(3):924. doi: 10.3390/jcm12030924.
6
Management of inadequate width of attached gingiva using mucograft.使用黏膜移植术治疗附着龈宽度不足
J Adv Pharm Technol Res. 2022 Nov;13(Suppl 1):S358-S361. doi: 10.4103/japtr.japtr_169_22. Epub 2022 Nov 30.
7
Clinical outcomes of root coverage using porcine-derived collagen matrix with modified coronally advanced tunnel technique (MCAT) in multiple gingival recessions in smokers - a randomized controlled clinical trial.使用猪源胶原基质结合改良的冠向推进隧道技术（MCAT）治疗多个吸烟患者的牙龈退缩的临床效果：一项随机对照临床试验。
Clin Oral Investig. 2023 Mar;27(3):1101-1111. doi: 10.1007/s00784-022-04700-w. Epub 2022 Sep 4.
8
Recession coverage using the modified coronally advanced tunnel and connective tissue graft with or without enamel matrix derivative: 5-year results of a randomised clinical trial.采用改良的冠状推进隧道和结缔组织移植物联合或不联合 enamel matrix derivative 的再生性牙周治疗：一项随机临床试验的 5 年结果。
Clin Oral Investig. 2023 Jan;27(1):105-113. doi: 10.1007/s00784-022-04691-8. Epub 2022 Aug 25.
9
Treatment of multiple adjacent RT 1 gingival recessions with the modified coronally advanced tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: 9-year results of a split-mouth randomized clinical trial.改良冠向推进隧道（MCAT）技术联合胶原基质或腭侧结缔组织移植治疗多个相邻 RT1 型牙龈退缩：一项随机对照分牙区临床研究 9 年的结果。
Clin Oral Investig. 2022 Dec;26(12):7135-7142. doi: 10.1007/s00784-022-04674-9. Epub 2022 Aug 22.
10
A New Matrix for Soft Tissue Management.一种用于软组织管理的新型基质。
J Clin Med. 2022 Aug 1;11(15):4486. doi: 10.3390/jcm11154486.