Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, CA 94305-5719, USA.
Child Adolesc Psychiatr Clin N Am. 2012 Oct;21(4):753-71. doi: 10.1016/j.chc.2012.07.010.
Little is known about the neurobiological effects of psychotropic medications used in the treatment of children and adolescents diagnosed with a psychiatric disorder. This review provides a synopsis of the literature demonstrating the neural effects associated with exposure to psychotropic medication in youth using multimodal neuroimaging. The article concludes by illustrating how, taken together, these studies suggest that pharmacological interventions during childhood do indeed affect brain structure and function in a detectable manner, and the effects appear to be ameliorative.
目前对于用于治疗儿童和青少年精神障碍的精神药物的神经生物学效应知之甚少。本综述提供了使用多模态神经影像学研究表明与青少年接触精神药物相关的神经效应的文献摘要。文章最后说明,这些研究表明,儿童时期的药物干预确实以可检测的方式影响大脑结构和功能,而且这些影响似乎是有益的。