Department of Psychiatry, Tufts University School of Medicine, Boston, MA 02111, USA.
Child Adolesc Psychiatr Clin N Am. 2012 Oct;21(4):957-73. doi: 10.1016/j.chc.2012.07.006.
Children with autism spectrum disorder present with a high rate of maladaptive behaviors and comorbid psychopathology. Psychopharmacologic treatment is frequently used in this population and is particularly associated with comorbid mental illness and increasing age. Successful treatment of presenting problems, however, is most likely achieved through consideration of multiple potential etiologic factors, only some of which may respond to pharmacologic intervention. The evidence base for targeting specific symptoms and disorders with psychopharmacology in children with autism spectrum disorder is expanding rapidly and offers guidance for practicing clinicians. The current evidence for symptom-specific treatment is presented.
自闭症谱系障碍儿童表现出较高的适应不良行为和共病精神病理学。该人群经常使用精神药理学治疗，特别是与共病精神疾病和年龄增长有关。然而，要成功治疗现有问题，最有可能考虑多种潜在的病因因素，其中只有一些可能对药物干预有反应。自闭症谱系障碍儿童使用精神药理学针对特定症状和障碍的证据基础正在迅速扩展，并为临床医生提供了指导。目前提出了针对特定症状的治疗的证据。
