Department of Psychiatry, Hoboken University Medical Center, 308 Willow Avenue, Hoboken, NJ 07030, USA.
Pediatr Clin North Am. 2012 Feb;59(1):175-87, xii. doi: 10.1016/j.pcl.2011.10.005.
At present, no evidence-based effective pharmacologic options are available for treating the core deficits of autism spectrum disorders (ASDs), which are best addressed by behavioral and educational interventions. However, such evidence exists for several of the frequently associated/comorbid symptoms such as aggression and severe irritability, hyperactivity, and repetitive behaviors, which can become a major source of additional distress and interference in functioning. This article offers information on the psychopharmacology of ASD that is current, relevant, and organized in a user-friendly manner, to form a concise but informative reference guide for primary pediatric clinicians.
目前，针对自闭症谱系障碍（ASD）的核心缺陷，尚无循证有效的药物治疗选择，行为和教育干预是最佳治疗方法。然而，针对一些常见的共病症状，如攻击行为和严重的易激惹、多动和重复行为，已经有了一些有效的药物治疗方法，这些症状可能会成为额外的痛苦和功能障碍的主要来源。本文提供了 ASD 精神药理学的最新信息，以用户友好的方式组织和呈现，为初级儿科临床医生提供了简明但信息丰富的参考指南。
