Experimental Psychology Unit, Helmut Schmidt University, University of the Federal Armed Forces Hamburg, Hamburg, Germany.
Int J Psychophysiol. 2013 Jan;87(1):1-7. doi: 10.1016/j.ijpsycho.2012.09.012. Epub 2012 Oct 4.
The Mismatch Negativity (MMN), a component of the event-related potential (ERP), is elicited by a deviant following a series of standard stimuli. The present study addressed the question whether two deviants occurring successively in one hierarchically organized auditory object would elicit separate MMN responses. An example of such an object is a VC syllable (vowel+consonant). In a passive oddball protocol, the syllables [ɔx] and [ɛʃ] were presented both as standards and deviants so that both phonemes, the vowel and the consonant, changed in the respective deviant. Two negative responses were found in the deviant-minus-standard difference waves. Due to the latencies these effects could not be interpreted as separate MMN responses to the phonemic changes. Instead, the first effect (108ms) was taken as an N1 modulation whereas the second negativity (168ms) was interpreted as an MMN mainly reflecting the change of the initial vowel. Furthermore, the present data were statistically compared with related results from Steinberg et al. (2010a, b) obtained partly from the same stimuli presented in oddball blocks with simple mono-phonemic deviances due to changing vowels. Higher MMN amplitudes were found for the syllable [ɛʃ] in the present data compared to those previous findings. Although this difference was only present for one of the stimulus syllables, it is discussed as a possible indicator of an anticipatory MMN enhancement due to the predictability of the second change in the deviant of the present experiment.
失匹配负波（MMN）是事件相关电位（ERP）的一个成分，由一系列标准刺激后的偏差引发。本研究探讨了在一个层次组织的听觉对象中连续出现两个偏差是否会引发单独的 MMN 反应的问题。这样的对象的一个例子是 VC 音节（元音+辅音）。在被动的Oddball 协议中，音节 [ɔx] 和 [ɛʃ] 既作为标准也作为偏差呈现，因此两个音素，元音和辅音，在各自的偏差中都发生了变化。在偏差减去标准的差异波中发现了两个负响应。由于潜伏期，这些效应不能解释为对音素变化的单独 MMN 反应。相反，第一个效应（108ms）被认为是 N1 调制，而第二个负性效应（168ms）被解释为主要反映初始元音变化的 MMN。此外，本数据与 Steinberg 等人（2010a，b）的相关结果进行了统计学比较，这些结果部分来自于相同的刺激，以 Oddball 块呈现，由于元音变化而产生简单的单音偏差。与以前的发现相比，本研究中发现 [ɛʃ] 音节的 MMN 振幅更高。尽管这种差异仅在刺激音节之一中存在，但它被讨论为由于本实验偏差中第二个变化的可预测性而导致的预期 MMN 增强的可能指标。
