Kommoss F, Bibbo M, Talerman A
Department of Pathology and Cell Biology, Jefferson Medical College, Philadelphia, Pennsylvania.
Lab Invest. 1990 Feb;62(2):223-31.
Paraffin sections from 30 endodermal sinus (yolk sac) tumors were Feulgen-stained, and nuclear DNA content (ploidy) was assessed through DNA cytophotometry using the microTICAS image analysis system. The series consisted of 20 ovarian, 8 testicular, 1 sacrococcygeal, and 1 mediastinal tumors. Of the 30 endodermal sinus (yolk sac) tumors 29 were shown to be aneuploid, whereas the remaining tumor which exhibited the recently described primitive intestinal or enteric pattern was diploid and may thus be considered a neoplasm showing a somewhat higher degree of differentiation as compared to tumors showing the other histologic patterns of endodermal sinus (yolk sac) tumors.
对30例内胚窦（卵黄囊）瘤的石蜡切片进行福尔根染色，使用microTICAS图像分析系统通过DNA细胞光度法评估核DNA含量（倍性）。该系列包括20例卵巢肿瘤、8例睾丸肿瘤、1例骶尾部肿瘤和1例纵隔肿瘤。在这30例内胚窦（卵黄囊）瘤中，29例显示为非整倍体，而其余呈现最近描述的原始肠型或肠型模式的肿瘤为二倍体，因此与显示内胚窦（卵黄囊）瘤其他组织学模式的肿瘤相比，可认为该肿瘤分化程度略高。
