Cunha Paulo Rowilson, Delfini Filho Oswaldo
Service of Dermatology, School of Medicine of Jundiaí, Sao Paulo, Brazil.
An Bras Dermatol. 2012 Sep-Oct;87(5):735-41. doi: 10.1590/s0365-05962012000500011.
Pruritus is a symptom that may be associated with a wide array of diseases - skin diseases, systemic diseases or even those without a defined cause. According to its severity and evolution, it may compromise the patients' quality of life in a significant way. New therapeutic approaches, in which histamine release is not the main event, are being described for pruritus control. Therefore, taking into account the origin of the mediators of pruritus, we conducted a review of the available resources emphasizing that, although very important, anti-histamines are not the answer for every kind of pruritus.
瘙痒是一种可能与多种疾病相关的症状——皮肤病、全身性疾病，甚至是那些病因不明的疾病。根据其严重程度和发展情况，它可能会严重影响患者的生活质量。目前正在描述一些新的治疗方法，其中组胺释放并非主要因素，用于控制瘙痒。因此，考虑到瘙痒介质的来源，我们对现有资源进行了综述，强调尽管抗组胺药非常重要，但并非对每种瘙痒都有效。
