• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿科人群细菌性脑膜炎的诊断与管理:综述

Diagnosis and management of bacterial meningitis in the paediatric population: a review.

作者信息

Tacon Catherine L, Flower Oliver

机构信息

Sydney Children's Hospital, Randwick, NSW, Australia.

出版信息

Emerg Med Int. 2012;2012:320309. doi: 10.1155/2012/320309. Epub 2012 Sep 20.

DOI:10.1155/2012/320309
PMID:23050153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3461291/
Abstract

Paediatric bacterial meningitis is a neurological emergency which, despite advances in medical management, still has a significant morbidity and mortality. Over recent decades new vaccines have led to a change in epidemiology of the disease; however, it remains a condition that requires a high index of suspicion, prompt diagnosis, and early management in the emergency department. New laboratory techniques and clinical tools are aiding the diagnosis of bacterial meningitis, yet some controversies still exist in its management. This paper outlines the changing epidemiology of the disease, current diagnostic techniques as well as controversies and advances in the management of bacterial meningitis in the paediatric population.

摘要

小儿细菌性脑膜炎是一种神经系统急症,尽管在医疗管理方面取得了进展,但仍具有较高的发病率和死亡率。近几十年来,新疫苗导致了该疾病流行病学的变化;然而,它仍然是一种在急诊科需要高度怀疑、及时诊断和早期管理的病症。新的实验室技术和临床工具有助于细菌性脑膜炎的诊断,但在其管理方面仍存在一些争议。本文概述了该疾病不断变化的流行病学、当前的诊断技术以及小儿细菌性脑膜炎管理方面的争议和进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24f/3461291/573264a34f78/EMI2012-320309.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24f/3461291/573264a34f78/EMI2012-320309.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24f/3461291/573264a34f78/EMI2012-320309.001.jpg

相似文献

1
Diagnosis and management of bacterial meningitis in the paediatric population: a review.儿科人群细菌性脑膜炎的诊断与管理:综述
Emerg Med Int. 2012;2012:320309. doi: 10.1155/2012/320309. Epub 2012 Sep 20.
2
Management of Acute Bacterial Meningitis in Children.儿童急性细菌性脑膜炎的管理
Infect Drug Resist. 2020 Nov 11;13:4077-4089. doi: 10.2147/IDR.S240162. eCollection 2020.
3
Acute bacterial meningitis in infants and children: epidemiology and management.婴幼儿急性细菌性脑膜炎:流行病学与治疗。
Paediatr Drugs. 2011 Dec 1;13(6):385-400. doi: 10.2165/11593340-000000000-00000.
4
Controversies in the management of bacterial meningitis.细菌性脑膜炎治疗中的争议
Paediatr Child Health. 2002 Sep;7(7):449-53. doi: 10.1093/pch/7.7.449.
5
Acute bacterial meningitis.急性细菌性脑膜炎
Emerg Med Clin North Am. 2008 May;26(2):281-317, viii. doi: 10.1016/j.emc.2008.02.002.
6
Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis.细菌结合疫苗时代儿童的脑脊液细胞增多症:区分细菌性和无菌性脑膜炎患儿
Pediatr Emerg Care. 2009 Feb;25(2):112-7; quiz 118-20. doi: 10.1097/PEC.0b013e318196faeb.
7
Post-Traumatic Meningitis Is a Diagnostic Challenging Time: A Systematic Review Focusing on Clinical and Pathological Features.创伤后脑膜炎是一个具有挑战性的诊断时期:一项侧重于临床和病理特征的系统评价。
Int J Mol Sci. 2020 Jun 10;21(11):4148. doi: 10.3390/ijms21114148.
8
Cryptococcal meningitis: a review for emergency clinicians.隐球菌性脑膜炎:急诊临床医生的综述。
Intern Emerg Med. 2021 Jun;16(4):1031-1042. doi: 10.1007/s11739-020-02619-2. Epub 2021 Jan 9.
9
[Acute care of patients with bacterial meningitis].[细菌性脑膜炎患者的急性护理]
Med Klin Intensivmed Notfmed. 2016 Apr;111(3):215-23. doi: 10.1007/s00063-015-0021-3. Epub 2015 Apr 16.
10
Serum procalcitonin in bacterial & non-bacterial meningitis in children.血清降钙素原在儿童细菌性和非细菌性脑膜炎中的应用。
BMC Pediatr. 2018 Nov 2;18(1):342. doi: 10.1186/s12887-018-1314-5.

引用本文的文献

1
Pneumolysin contributes to dysfunction of nasal epithelial barrier for promotion of pneumococcal dissemination into brain tissue.肺炎球菌溶血素有助于破坏鼻上皮屏障功能,从而促进肺炎球菌向脑组织扩散。
mSphere. 2024 Oct 29;9(10):e0065524. doi: 10.1128/msphere.00655-24. Epub 2024 Sep 30.
2
Subdural Empyema in Pediatric Bacterial Meningitis: A Case Report.小儿细菌性脑膜炎并发硬脑膜下积脓:一例报告
Cureus. 2023 Dec 31;15(12):e51401. doi: 10.7759/cureus.51401. eCollection 2023 Dec.
3
Delays in Time-To-Antibiotics for Young Febrile Infants With Serious Bacterial Infections: A Prospective Single-Center Study.

本文引用的文献

1
Immunogenicity and tolerability of recombinant serogroup B meningococcal vaccine administered with or without routine infant vaccinations according to different immunization schedules: a randomized controlled trial.根据不同免疫计划,与常规婴儿疫苗联合或不联合使用时重组 B 群脑膜炎球菌疫苗的免疫原性和耐受性:一项随机对照试验。
JAMA. 2012 Feb 8;307(6):573-82. doi: 10.1001/jama.2012.85.
2
Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b/3 randomised, observer-blind, placebo-controlled study.在智利健康青少年中,一种包含多种脑膜炎奈瑟菌 B 群(4CMenB)组份的疫苗的免疫原性和耐受性:一项 2b/3 期、随机、观察者盲、安慰剂对照研究。
Lancet. 2012 Feb 18;379(9816):617-24. doi: 10.1016/S0140-6736(11)61713-3. Epub 2012 Jan 18.
3
患有严重细菌感染的发热婴幼儿使用抗生素的时间延迟:一项前瞻性单中心研究。
Front Pediatr. 2022 Apr 29;10:873043. doi: 10.3389/fped.2022.873043. eCollection 2022.
4
Pyrexia in a young infant - is height of fever associated with serious bacterial infection?发热的婴儿-高热是否与严重细菌感染有关?
BMC Pediatr. 2022 Apr 8;22(1):188. doi: 10.1186/s12887-022-03264-8.
5
Metagenomic Next-Generation Sequencing for Diagnosis of Pediatric Meningitis and Encephalitis: A Review.宏基因组下一代测序在儿童脑膜炎和脑炎诊断中的应用:综述
J Pediatric Infect Dis Soc. 2021 Dec 24;10(Supplement_4):S78-S87. doi: 10.1093/jpids/piab067.
6
Clinical Features and Outcomes of Streptococcus pneumoniae Meningitis in Children: A Retrospective Analysis of 26 Cases in China.中国 26 例儿童肺炎链球菌性脑膜炎的临床特征和转归:一项回顾性分析。
Neuropediatrics. 2022 Feb;53(1):32-38. doi: 10.1055/s-0041-1728655. Epub 2021 Oct 13.
7
Blood Procalcitonin Level as a Diagnostic Marker of Pediatric Bacterial Meningitis: A Systematic Review and Meta-Analysis.血降钙素原水平作为儿童细菌性脑膜炎的诊断标志物:一项系统评价和荟萃分析
Diagnostics (Basel). 2021 May 8;11(5):846. doi: 10.3390/diagnostics11050846.
8
Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda): Observational Cohort Study Protocol of the "PI-POC" Trial.资源匮乏地区(乌干达西南部)脑膜炎诊断的即时检测方法:“PI-POC”试验的观察性队列研究方案
JMIR Res Protoc. 2020 Nov 4;9(11):e21430. doi: 10.2196/21430.
9
Rapid Diagnosis of Meningococcal Meningitis in a Patient With Familial Mediterranean Fever by the FilmArray Meningitis/Encephalitis Panel: A Case Report.通过FilmArray脑膜炎/脑炎检测板快速诊断一名患有家族性地中海热患者的脑膜炎球菌性脑膜炎:病例报告
Neurohospitalist. 2020 Oct;10(4):297-300. doi: 10.1177/1941874420908421. Epub 2020 Mar 25.
10
Comparison of acridine orange fluorescent microscopy and gram stain light microscopy for the rapid detection of bacteria in cerebrospinal fluid.吖啶橙荧光显微镜检查与革兰氏染色光学显微镜检查在脑脊液细菌快速检测中的比较
BMC Res Notes. 2020 Jan 13;13(1):29. doi: 10.1186/s13104-020-4895-7.
5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: a double-blind randomised equivalence study.头孢曲松治疗儿童细菌性脑膜炎 5 天与 10 天疗程的双盲随机等效性研究。
Lancet. 2011 May 28;377(9780):1837-45. doi: 10.1016/S0140-6736(11)60580-1.
4
Serum procalcitonin in viral and bacterial meningitis.病毒性和细菌性脑膜炎中的血清降钙素原
J Glob Infect Dis. 2011 Jan;3(1):14-8. doi: 10.4103/0974-777X.77290.
5
Diagnostic accuracy of cerebrospinal fluid lactate for differentiating bacterial meningitis from aseptic meningitis: a meta-analysis.脑脊液乳酸诊断细菌性脑膜炎与无菌性脑膜炎的准确性:荟萃分析。
J Infect. 2011 Apr;62(4):255-62. doi: 10.1016/j.jinf.2011.02.010. Epub 2011 Mar 5.
6
Which early 'red flag' symptoms identify children with meningococcal disease in primary care?哪些早期“红色预警”症状可在初级保健中识别出脑膜炎奈瑟菌病患儿?
Br J Gen Pract. 2011 Mar;61(584):e97-104. doi: 10.3399/bjgp11X561131.
7
Diagnostic accuracy of clinical symptoms and signs in children with meningitis.儿童脑膜炎临床症状和体征的诊断准确性。
Pediatr Emerg Care. 2011 Mar;27(3):196-9. doi: 10.1097/PEC.0b013e31820d6543.
8
Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial.在马拉维高 HIV 血清流行率环境中,对细菌性脑膜炎成人患者采用甘油辅助治疗:一项双盲、随机对照试验。
Lancet Infect Dis. 2011 Apr;11(4):293-300. doi: 10.1016/S1473-3099(10)70317-0. Epub 2011 Feb 18.
9
Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis.脑脊液乳酸浓度鉴别细菌性脑膜炎与无菌性脑膜炎:系统评价和荟萃分析。
Crit Care. 2010;14(6):R240. doi: 10.1186/cc9395. Epub 2010 Dec 31.
10
Clinical features suggestive of meningitis in children: a systematic review of prospective data.儿童脑膜炎的临床特征:前瞻性数据的系统评价。
Pediatrics. 2010 Nov;126(5):952-60. doi: 10.1542/peds.2010-0277. Epub 2010 Oct 25.