GWASTools：一个用于全基因组关联研究质量控制和分析的 R/Bioconductor 包。
GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studies.
机构信息
Department of Biostatistics, University of Washington, Seattle, WA, USA.
出版信息
Bioinformatics. 2012 Dec 15;28(24):3329-31. doi: 10.1093/bioinformatics/bts610. Epub 2012 Oct 10.
Abstract
GWASTools is an R/Bioconductor package for quality control and analysis of genome-wide association studies (GWAS). GWASTools brings the interactive capability and extensive statistical libraries of R to GWAS. Data are stored in NetCDF format to accommodate extremely large datasets that cannot fit within R's memory limits. The documentation includes instructions for converting data from multiple formats, including variants called from sequencing. GWASTools provides a convenient interface for linking genotypes and intensity data with sample and single nucleotide polymorphism annotation.
摘要
GWASTools 是一个用于全基因组关联研究（GWAS）质量控制和分析的 R/Bioconductor 包。GWASTools 为 GWAS 带来了 R 的交互功能和广泛的统计库。数据以 NetCDF 格式存储，以适应无法容纳在 R 内存限制内的极大数据集。文档包括从多种格式转换数据的说明，包括从测序调用的变体。GWASTools 为链接基因型和强度数据与样本和单核苷酸多态性注释提供了一个方便的接口。
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