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现代欧洲人的祖先:古 DNA 的贡献。

Ancestry of modern Europeans: contributions of ancient DNA.

机构信息

Laboratoire AMIS, CNRS UMR 5288, 37 Allées Jules Guesde,Toulouse cedex 3, France.

出版信息

Cell Mol Life Sci. 2013 Jul;70(14):2473-87. doi: 10.1007/s00018-012-1180-5. Epub 2012 Oct 11.

DOI:10.1007/s00018-012-1180-5
PMID:23052219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11113793/
Abstract

Understanding the peopling history of Europe is crucial to comprehend the origins of modern populations. Of course, the analysis of current genetic data offers several explanations about human migration patterns which occurred on this continent, but it fails to explain precisely the impact of each demographic event. In this context, direct access to the DNA of ancient specimens allows the overcoming of recent demographic phenomena, which probably highly modified the constitution of the current European gene pool. In recent years, several DNA studies have been successfully conducted from ancient human remains thanks to the improvement of molecular techniques. They have brought new fundamental information on the peopling of Europe and allowed us to refine our understanding of European prehistory. In this review, we will detail all the ancient DNA studies performed to date on ancient European DNA from the Middle Paleolithic to the beginning of the protohistoric period.

摘要

了解欧洲的人群历史对于理解现代人口的起源至关重要。当然,对当前遗传数据的分析提供了有关该大陆发生的人类迁移模式的几种解释,但它无法准确解释每个人口事件的影响。在这种情况下,直接访问古代样本的 DNA 可以克服最近的人口现象,这些现象可能极大地改变了当前欧洲基因库的构成。近年来,由于分子技术的改进,从古代人类遗骸中成功进行了几项 DNA 研究。它们提供了有关欧洲殖民化的新基础信息,并使我们能够更深入地了解欧洲史前史。在这篇综述中,我们将详细介绍迄今为止对从中石器时代到原始历史初期的欧洲古代 DNA 进行的所有古代 DNA 研究。

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本文引用的文献

1
Effect of ancient population structure on the degree of polymorphism shared between modern human populations and ancient hominins.古代人口结构对现代人类群体与古代原始人类之间共享多态性程度的影响。
Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):13956-60. doi: 10.1073/pnas.1200567109. Epub 2012 Aug 14.
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Am J Phys Anthropol. 2012 Aug;148(4):571-9. doi: 10.1002/ajpa.22074. Epub 2012 May 3.
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Science. 2012 Apr 27;336(6080):466-9. doi: 10.1126/science.1216304.
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Archaeology. Ancient migrants brought farming way of life to Europe.考古学。古代移民将农耕生活方式带到了欧洲。
Science. 2012 Apr 27;336(6080):400-1. doi: 10.1126/science.336.6080.400.
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New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing.全基因组测序揭示蒂罗尔冰人的起源和表型新见解。
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