Kaiser T, Thiery J
Institut für Laboratoriumsmedizin, Klinische Chemie und Molekulare Diagnostik, Universitätsklinikum Leipzig, Liebigstr. 27, 04103, Leipzig, Deutschland.
Herz. 2012 Nov;37(7):773-82. doi: 10.1007/s00059-012-3683-0.
Cardiovascular diseases are the main cause of mortality for patients with advanced age. Changes in lipid metabolism are common and play an important role as key risk factors. This article explains an approach in the diagnostics of dyslipidemia according to the current guidelines. First, the overall risk evaluation of cardiovascular mortality based on the current chart has to be evaluated. Depending on these results an individual LDL-C goal should be defined. The article also includes other relevant cardiovascular risk factors which were not included in the established risk charts. Furthermore, the main innovative biomarkers are discussed in their possible applications and diagnostic value.
心血管疾病是老年患者死亡的主要原因。脂质代谢变化很常见，作为关键风险因素发挥着重要作用。本文根据当前指南解释了一种血脂异常的诊断方法。首先，必须根据当前图表评估心血管死亡的总体风险。根据这些结果应确定个体低密度脂蛋白胆固醇（LDL-C）目标。本文还包括既定风险图表中未涵盖的其他相关心血管风险因素。此外，还讨论了主要创新生物标志物的可能应用和诊断价值。
