Sicras-Mainar Antonio, Navarro-Artieda Ruth, Ibáñez-Nolla Jordi, Pérez-Ronco Julián
Direccion de Planificacion y Desarrollo Organizativo, Badalona, España.
Rev Neurol. 2012 Oct 16;55(8):449-61.
To determine the incidence rate, the treatment administered and the use of health resources and health, and their respective costs in patients with postherpetic neuralgia (PHN).
We performed an observational design, made from retrospective review of patient records from six primary care centers and one hospital. All patients > 30 years consulting for PHN between 1/1/2007 and 31/12/2010 were included. Prepared two study groups according to presence / absence of PHN. Follow up was for one year.
socio-demographic, treatment and co-morbidity. The cost model differed direct healthcare costs (primary care/specialist) and indirect (productivity).
logistic regression models and analysis of covariance (p < 0.05).
1506 patients were recruited, age: 61.2 years female: 59.2%. 15.1% (n = 228, 95% CI = 8.1-22.1%) had a PHN (incidence rate: 0.8/1,000 inhabitants/year; 95% CI = 0.7-0.9/1,000 population/year), and increased with age (≥ 65 years: 19.7%). The PHN was principally associated with: psychosis (OR = 3.9), dementia (OR = 2.3), depression (OR = 1.8) and age (OR = 1.1), p < 0.03. Drugs use was higher (5.3 vs. 3.3; p < 0.001). The cost in primary care was 63.1% and 24.7% indirect. Total cost €1827.1 vs. €457.5 (p = 0.003), respectively, due to higher labour productivity losses (€692.2 vs. €62.4) and health costs (€1135 vs. €395.1); p < 0.001. All cost components maintained these differences.
PHN is a frequent complication. These patients have a significant economic burden. The cost increases with age.
确定带状疱疹后神经痛（PHN）患者的发病率、所接受的治疗、卫生资源及医疗保健的使用情况及其各自的费用。
我们采用观察性设计，通过回顾六个初级保健中心和一家医院的患者记录进行研究。纳入2007年1月1日至2010年12月31日期间因PHN前来就诊的所有年龄大于30岁的患者。根据是否患有PHN准备了两个研究组。随访为期一年。
社会人口统计学、治疗及合并症情况。成本模型区分了直接医疗费用（初级保健/专科治疗）和间接费用（生产力）。
逻辑回归模型和协方差分析（p<0.05）。
共招募了1506名患者，年龄61.2岁，女性占59.2%。15.1%（n = 228，95%CI = 8.1 - 22.1%）患有PHN（发病率：0.8/1000居民/年；95%CI = 0.7 - 0.9/1000人口/年），且发病率随年龄增加而升高（≥65岁：19.7%）。PHN主要与以下因素相关：精神病（OR = 3.9）、痴呆（OR = 2.3）、抑郁症（OR = 1.8）和年龄（OR = 1.1），p<0.03。药物使用频率更高（5.3对3.3；p<0.001）。初级保健费用占63.1%，间接费用占24.7%。总成本分别为1827.1欧元对457.5欧元（p = 0.003），这是由于更高的劳动生产率损失（692.2欧元对62.4欧元）和医疗费用（1135欧元对395.1欧元）所致；p<0.001。所有成本构成部分均保持这些差异。
PHN是一种常见并发症。这些患者有显著的经济负担。成本随年龄增加而上升。
