Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, Suita, Japan.
Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11363-6. doi: 10.1002/anie.201206115. Epub 2012 Oct 10.
Where HAS you been? A manganese-mediated annulation of 2-isocyanobiaryls with organoboronic acids is developed for the synthesis of a broad range of phenanthridine derivatives. Mechanistic studies indicate that the reaction proceeds by the intramolecular homolytic aromatic substitution (HAS) of an imidoyl radical intermediate.
你去哪儿了？本文开发了一种锰介导的 2-异氰基二芳基与有机硼酸的环化反应，用于合成广泛的菲啶衍生物。机理研究表明，该反应是通过亚胺自由基中间体的分子内自由基取代（HAS）进行的。
