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高危大量非静脉曲张性上消化道出血患者的血管造影检查

Angiography in poor-risk patients with massive nonvariceal upper gastrointestinal bleeding.

作者信息

Dempsey D T, Burke D R, Reilly R S, McLean G K, Rosato E F

机构信息

Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia.

出版信息

Am J Surg. 1990 Mar;159(3):282-6. doi: 10.1016/s0002-9610(05)81218-8.

Abstract

The purpose of this retrospective study was to determine the diagnostic and therapeutic usefulness of gut angiography in patients with massive upper gastrointestinal bleeding from a nonvariceal source. All patients (n = 64) in this category who underwent a gut angiogram between 1980 and 1986 were studied. Pre-angiogram endoscopy was attempted in all patients and was nondiagnostic in 14 (22%). Contrast extravasation at angiography was seen in 25 of 64 patients (39%), and in over half of these patients endoscopy was nondiagnostic (n = 11) or wrong (n = 3). Attempts to control bleeding in this group by selective arterial embolization (n = 14) or intra-arterial vasopressin (n = 11) successfully averted operation in 13 of 25 patients (52%) and was associated with a 50% reduction in mortality (83% versus 38%). Selective embolization of vessels thought to be bleeding on clinical grounds without evidence of contrast extravasation (i.e., "blind" embolization) was not helpful in controlling hemorrhage. Urgent gut angiography in patients with massive upper gastrointestinal bleeding of arteriocapillary source is a useful diagnostic and therapeutic maneuver and warrants continued application in this group of poor-risk patients.

摘要

这项回顾性研究的目的是确定肠道血管造影术对非静脉曲张性上消化道大出血患者的诊断和治疗价值。对1980年至1986年间接受肠道血管造影的此类所有患者(n = 64)进行了研究。所有患者均尝试在血管造影术前进行内镜检查,其中14例(22%)检查结果未明确诊断。64例患者中有25例(39%)在血管造影时可见造影剂外渗,其中超过半数患者的内镜检查未明确诊断(n = 11)或诊断错误(n = 3)。通过选择性动脉栓塞(n = 14)或动脉内注射血管加压素(n = 11)来控制该组患者出血的尝试,成功避免了25例患者中13例(52%)的手术,并使死亡率降低了50%(从83%降至38%)。在无造影剂外渗证据的情况下,基于临床判断对疑似出血血管进行选择性栓塞(即“盲目”栓塞)对控制出血并无帮助。对于动脉毛细血管源性上消化道大出血患者,紧急肠道血管造影术是一种有用的诊断和治疗手段,值得在这类高危患者中继续应用。

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