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[同时进行颈动脉和冠状动脉手术——风险归因于什么?]

[Simultaneous operations on the carotid and coronary arteries - the risk is due to?].

作者信息

Bazylev V V, Chernogrivov A E, Voevodin A B

出版信息

Angiol Sosud Khir. 2012;18(3):106-15.

PMID:23059614
Abstract

The article deals with the findings of a retrospective study regarding the incidence of risk factors for unfavourable outcomes during interventions on coronary arteries in patients presenting with atherosclerotic lesions of the carotid basin as compared to aortocoronary bypass grafting alone, followed by analysing individual risk factors. Also evaluated herein is the incidence rate of complications after coronary bypass grafting in patients presenting with various concomitant pathology, followed by determining the relative risk influencing hospital mortality both by groups as a whole and with due regard for stratification along the most significant risk factors. The study comprised a total of 74 patients with combined atherosclerotic lesions of carotid and coronary arteries, who were simultaneously subjected to revascularization of the myocardium and carotid basin. The control group was composed of 1,128 patients undergoing coronary bypass grafting alone. All patients were treated at the Federal Centre for Cardiovascular Surgery under the Russian Federation Ministry of Public Health and Social Development (Penza) from October 2008 to December 2011. The obtained findings confirmed the proposition that a simultaneous intervention of the CA does not increase the postoperative complications rate. The method of stratification demonstrated that the risk for the development of lethal outcomes in such patients turned out considerably higher. Patients with CA stenosis run higher risks of operational vascular complications, which is confirmed by a comparable level of mortality, cerebral strokes and myocardial infarction with the stratified group of patients having similar incidence of risk factors. Preventive interventions on the CA are aimed at decreasing operative complications and bring no additional risk to the lethality rate.

摘要

本文探讨了一项回顾性研究的结果,该研究涉及患有颈动脉粥样硬化病变的患者在冠状动脉干预过程中不良结局危险因素的发生率,并与单纯主动脉冠状动脉搭桥术进行比较,随后分析个体危险因素。本文还评估了患有各种合并症的患者冠状动脉搭桥术后并发症的发生率,随后确定总体上各群体以及考虑到最重要危险因素分层情况下影响医院死亡率的相对风险。该研究共纳入74例合并颈动脉和冠状动脉粥样硬化病变的患者,他们同时接受了心肌和颈动脉血管重建术。对照组由1128例仅接受冠状动脉搭桥术的患者组成。所有患者于2008年10月至2011年12月在俄罗斯联邦卫生部和社会发展部下属的联邦心血管外科中心(奔萨)接受治疗。获得的研究结果证实了冠状动脉同期干预不会增加术后并发症发生率这一观点。分层方法表明,此类患者发生致命结局的风险要高得多。冠状动脉狭窄患者发生手术血管并发症的风险更高,这一点通过死亡率、脑卒中和心肌梗死的可比水平得到证实,与危险因素发生率相似的分层患者组情况相同。对冠状动脉的预防性干预旨在降低手术并发症,且不会给致死率带来额外风险。

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