Department of Ophthalmology, Faculty of Medicine, Ege University, Izmir, Turkey.
J Ocul Pharmacol Ther. 2013 Apr;29(3):349-52. doi: 10.1089/jop.2012.0145. Epub 2012 Oct 12.
This study aims to investigate the effects of tropicamide 1% on the main numerical parameters of anterior segment with the Pentacam rotating Scheimpflug camera in healthy individuals.
Pentacam measurements of 50 (25 female and 25 male) healthy individuals before and after 25 min of tropicamide 1% instillation were performed and compared. For comparison of the test parameters, paired t-test was used in the groups.
Mean age in the study group was 28.40±4.58 years (range 18-35 years). Measurements between 2 sessions were significantly different for the parameters of anterior chamber depth (ACD) and anterior chamber volume (ACV) (P<0.05).
Tropicamide 1% instillation leads to a significant increment in ACD and ACV measurements. Effects of tropicamide on these parameters for Pentacam measurements should be considered to ensure exact clinical interpretation in ophthalmologic practice.
本研究旨在使用 Pentacam 旋转式 Scheimpflug 相机，评估 1%托吡卡胺滴眼后对健康个体眼前节主要数值参数的影响。
对 50 名（25 名女性和 25 名男性）健康个体使用 Pentacam 进行测量，分别在使用 1%托吡卡胺滴眼前和滴眼后 25 分钟进行测量，并对测量结果进行比较。采用配对 t 检验对两组测试参数进行比较。
研究组的平均年龄为 28.40±4.58 岁（18-35 岁）。两次测量之间的前房深度（ACD）和前房容积（ACV）参数存在显著差异（P<0.05）。
1%托吡卡胺滴眼后可显著增加 ACD 和 ACV 的测量值。在眼科临床实践中，为确保准确的临床解读，应考虑托吡卡胺对这些参数测量值的影响。
