Faculty of Medicine, Department of Ophthalmology, Ege University, Izmir, Turkey.
Acta Ophthalmol. 2011 Aug;89(5):e461-5. doi: 10.1111/j.1755-3768.2011.02122.x. Epub 2011 Feb 21.
To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children.
Ege University Faculty of Medicine, Department of Ophthalmology.
Pentacam measurements of 50 (23 boys and 27 girls) children before and after 45 min of cyclopentolate hydrochloride 1% instillation were performed and compared with 31 (17 boys and 14 girls) no medication instilled control group. Measurements of the control group (cycloplegia-free) were taken at two separate sessions with 45-min intervals. For comparison of the test parameters, paired t-test in the groups and unpaired t-test in between the groups were used.
Mean ages in the study and control groups were 10.06 ± 2.87 (range 6 and 16 years) and 9.87 ± 2.72 (range 6 and 16 years), respectively, and the difference was statistically insignificant (p > 0.05). In the study group, measurements between two sessions were significantly different for the parameters of anterior chamber depth (ACD), anterior chamber volume (ACV) and central corneal thickness (CCT) (p < 0.05), whereas none of the parameters was different between two sessions for control group.
Cyclopentolate hydrochloride 1% instillation leads to significant decrement in CCT. ACD and ACV are the other important refractive parameters that increase significantly after cycloplegia. Effects of cycloplegia on these parameters for Pentacam measurements should be regarded for proper clinical interpretation in children.
研究盐酸环喷托酯 1%对 Pentacam 旋转式 Scheimpflug 眼前节分析仪主要数值参数的影响。
伊兹密尔大学医学院眼科。
对 50 例（23 名男性和 27 名女性）儿童使用盐酸环喷托酯 1%滴眼 45 分钟前后的 Pentacam 测量值进行了研究，并与 31 例（17 名男性和 14 名女性）未滴注药物的对照组进行了比较。对照组（无睫状肌麻痹）在两次间隔 45 分钟的单独检查中进行了测量。为了比较测试参数，对组内进行配对 t 检验，对组间进行独立 t 检验。
研究组和对照组的平均年龄分别为 10.06 ± 2.87（范围 6 至 16 岁）和 9.87 ± 2.72（范围 6 至 16 岁），差异无统计学意义（p > 0.05）。在研究组中，两次检查之间的参数有显著差异，包括前房深度（ACD）、前房容积（ACV）和中央角膜厚度（CCT）（p < 0.05），而对照组两次检查之间的参数没有差异。
盐酸环喷托酯 1%滴眼可导致 CCT 显著下降。ACD 和 ACV 是其他重要的屈光参数，在睫状肌麻痹后显著增加。在儿童中，对于 Pentacam 测量，应考虑睫状肌麻痹对这些参数的影响，以便进行适当的临床解释。
