Arici Ceyhun, Turk Adem, Ceylan Osman Melih, Kola Mehmet, Hurmeric Volkan
Department of Ophthalmology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Department of Ophthalmology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Arq Bras Oftalmol. 2014 Aug;77(4):228-32. doi: 10.5935/0004-2749.20140059.
To investigate the effects of topically applied 1% cyclopentolate hydrochloride on anterior segment parameters obtained with a Pentacam rotating Scheimpflug camera in healthy young adults.
Anterior segment analyses of 25 eyes from 25 young adults (Group 1), before and after 45 min of 1% cyclopentolate hydrochloride application, were performed. For a control group (cycloplegia-free, Group 2), 24 eyes of 24 age- and sex-matched healthy cases were evaluated twice at 45 min intervals. The results obtained from the groups were compared statistically.
The mean ages of the groups were 23.04 ± 3.42 (range, 18-29) and 22.4 ± 2.05 (range, 18-27) years for Groups 1 and 2, respectively (p=0.259). In Group 1, measurements between the two analyses were significantly different for the values of anterior chamber depth (ACD), anterior chamber angle (ACA), and anterior chamber volume (ACV) (p<0.05), whereas no statistical difference was found for the central corneal thickness (CCT) and keratometry (K1, K2) measurements. In Group 2, none of these parameters were statistically different between the two analyses.
Topically applied 1% cyclopentolate hydrochloride caused an increase in the ACD and ACV values, and a decrease in the ACA value. However, it had no significant effect on the CCT and keratometry measurements. It is important to consider these effects when using the Pentacam device on young adults with cycloplegia and when applying it for various reasons.
研究局部应用1%盐酸环喷托酯对健康年轻成年人使用Pentacam旋转式Scheimpflug相机获得的眼前节参数的影响。
对25名年轻成年人（第1组）的25只眼在应用1%盐酸环喷托酯45分钟前后进行眼前节分析。对于对照组（未散瞳，第2组），对24名年龄和性别匹配的健康受试者的24只眼每隔45分钟进行两次评估。对两组获得的结果进行统计学比较。
第1组和第2组的平均年龄分别为23.04±3.42岁（范围18 - 29岁）和22.4±2.05岁（范围18 - 27岁）（p = 0.259）。在第1组中，两次分析之间前房深度（ACD）、前房角（ACA）和前房容积（ACV）值的测量有显著差异（p < 0.05），而中央角膜厚度（CCT）和角膜曲率测量（K1、K2）没有统计学差异。在第2组中，两次分析之间这些参数均无统计学差异。
局部应用1%盐酸环喷托酯导致ACD和ACV值增加，ACA值降低。然而，它对CCT和角膜曲率测量没有显著影响。在对有睫状肌麻痹的年轻成年人使用Pentacam设备以及因各种原因应用该设备时，考虑这些影响很重要。
