Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert Einstein Str. 29a, 18059 Rostock, Germany.
J Am Chem Soc. 2012 Nov 7;134(44):18325-9. doi: 10.1021/ja3069165. Epub 2012 Oct 29.
Unprecedented chemoselective reductions of phosphine oxides to phosphines proceed smoothly in the presence of catalytic amounts of specific Brønsted acids. By utilizing inexpensive silanes, e.g., PMHS or (EtO)(2)MeSiH, other reducible functional groups such as ketones, aldehydes, olefins, nitriles, and esters are well-tolerated under optimized conditions.
在催化量的特定布朗斯台德酸存在下，膦氧化物可顺利进行前所未有的化学选择性还原为膦。通过利用廉价的硅烷，例如 PMHS 或（EtO）（2）MeSiH，在优化条件下，其他可还原官能团，如酮、醛、烯烃、腈和酯，也能很好地耐受。
