Nys P S, Abramova E E, Kolygina T S, Savitskaia E M
Antibiotiki. 1977 May;22(5):405-8.
Potentiometric titration was performed and the ioniziation macroconstants of D-(--)-alpha-aminophenylacetic acid and its methyl ether were determined. The constants were used for estimation of 4 microconstants of D-(--)-alpha-aminophenylacetic acid and the constants of the tautomeric equilibrium of the zwitter-ionic and neutral forms of the amino acid. Minimum solubility of D-(--)-alpha-aminophenylacetic acid was determined and pH-dependence of its solubility was estimated.
进行了电位滴定,并测定了D-(-)-α-氨基苯乙酸及其甲醚的电离宏观常数。这些常数用于估算D-(-)-α-氨基苯乙酸的4个微观常数以及该氨基酸两性离子和中性形式的互变异构平衡常数。测定了D-(-)-α-氨基苯乙酸的最低溶解度,并估算了其溶解度的pH依赖性。