Pattengale P K, Taylor C R, Panke T, Tatter D, McCormick R A, Rawlinson D G, Davis R L
Acta Neuropathol. 1979 Dec;48(3):165-9. doi: 10.1007/BF00690516.
This report presents the findings of a study of a 17-year-old male with a selective immunodeficiency to the Epstein-Barr virus, who died of a malignant lymphoma following clinical infectious mononucleosis. Autopsy findings and immunohistochemical techniques demonstrated a malignant lymphoma with B-lymphocyte characteristics which primarily involved the central nervous system (CNS). The relationship of the Epstein-Barr virus to lymphoproliferation is discussed.
本报告介绍了一名17岁男性的研究结果，该男性对爱泼斯坦-巴尔病毒存在选择性免疫缺陷，在临床传染性单核细胞增多症后死于恶性淋巴瘤。尸检结果和免疫组织化学技术显示，该恶性淋巴瘤具有B淋巴细胞特征，主要累及中枢神经系统（CNS）。文中讨论了爱泼斯坦-巴尔病毒与淋巴细胞增殖的关系。
