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睾丸癌根治性放疗后发生的胃癌

Adenocarcinoma of the stomach following radical radiotherapy for testicular cancer.

作者信息

Griffith C D, Chadderton R, Bourke J B

机构信息

Department of Surgery, Queen's Medical Centre, Nottingham, UK.

出版信息

Eur J Surg Oncol. 1990 Feb;16(1):68-9.

PMID:2307241
Abstract

Two male patients who underwent curative surgery and adjuvant radiotherapy (with further chemotherapy in one) for testicular cancer developed adenocarcinoma of the stomach 5 and 19 years after treatment. The stomach is included in the field of radiotherapy used to treat the para-aortic lymph nodes and this may lead to dysplastic changes in the stomach mucosa which can lead to frank malignancy. Early endoscopy should be offered to patients with dyspeptic symptoms after adjuvant radiotherapy for testicular cancer.

摘要

两名接受了睾丸癌根治性手术及辅助放疗(其中一人还接受了进一步化疗)的男性患者,在治疗后5年和19年分别发生了胃癌。胃包含在用于治疗腹主动脉旁淋巴结的放疗范围内,这可能导致胃黏膜发育异常改变,进而发展为明显的恶性肿瘤。对于接受睾丸癌辅助放疗后出现消化不良症状的患者,应尽早进行内镜检查。

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