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腰椎管狭窄症合并Ⅰ度退行性腰椎滑脱患者采用单侧入路显微外科双侧减压术后的临床疗效及影像学变化:至少3年随访结果

Clinical Outcomes and Radiologic Changes After Microsurgical Bilateral Decompression by a Unilateral Approach in Patients With Lumbar Spinal Stenosis and Grade I Degenerative Spondylolisthesis With a Minimum 3-Year Follow-Up.

作者信息

Jang Jun-Won, Park Jin-Hun, Hyun Seung-Jae, Rhim Seung-Chul

机构信息

*Department of Neurosurgery, Mokdong Himchanhospital, Mok-dong, Yangcheon-gu, Seoul†Department of Neurological Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung‡Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

出版信息

Clin Spine Surg. 2016 Aug;29(7):268-71. doi: 10.1097/BSD.0b013e31827566a8.

Abstract

STUDY DESIGN

A retrospective study.

OBJECTIVE

To analyze the clinical outcomes and radiologic changes after microsurgical bilateral decompression via a unilateral approach in patients with lumbar spinal stenosis (LSS) and degenerative spondylolisthesis (DS).

SUMMARY OF BACKGROUND DATA

Satisfactory short-term results have been observed after minimally invasive decompressive procedures, but intermediate-term and long-term outcomes have not been assessed. It is not yet clear whether decompressive laminectomy with concomitant fusion is the optimal surgical treatment for spinal stenosis combined with mild DS. We, therefore, evaluated minimum 3-year clinical outcomes and radiologic changes in patients with LSS and grade 1 DS, who underwent microsurgical bilateral decompression via a unilateral approach, without fusion.

METHODS

We assessed 21 consecutive patients who underwent surgery conducted by a single surgeon of our hospital, between 2005 and 2007. The Oswestry Disability Index was determined preoperatively, just before discharge, and at last follow-up. Plain dynamic x-rays were used to determine slip percentages.

RESULTS

Average patient age and clinical and radiologic follow-up periods were 67 years, 49.3 months, and 18 months, respectively. Preoperative, immediate postoperative, and last follow-up average Oswestry Disability Indices were 59.52±9.00, 50.19±7.23, and 26.19±12.42, respectively. However, 1 patient experienced aggravated symptoms and later underwent a fusion procedure. Of the 22 levels with spondylolisthesis, 15 had no sagittal motion as the difference in slip percentage on dynamic x-rays, but 7 showed sagittal motion. Average slip percentages increased from 13.90±5.41% to 14.60±5.78% for levels without sagittal motion on dynamic x-ray, and from 13.12±3.48% to 18.58±4.55% for levels with sagittal motion.

CONCLUSIONS

Despite small case series with retrospective design and the absence of a control group, our study suggests that bilateral decompression via a unilateral approach in patients with LSS and grade 1 DS showed good mid-term clinical outcomes, despite an increase in slip percentage.However, more marked increases in slippage were observed in patients with sagittal motion in spondylolisthesis levels on preoperative dynamic x-ray, than in patients without sagittal motion. Therefore, bilateral decompression via a unilateral approach can aggravate symptoms related to instability in patients with preoperative sagittal motion on dynamic x-ray, and needs a longer term follow-up than in our study.

摘要

研究设计

一项回顾性研究。

目的

分析腰椎管狭窄症(LSS)和退行性椎体滑脱(DS)患者经单侧入路进行双侧显微减压术后的临床疗效和影像学变化。

背景资料总结

微创减压手术后观察到了满意的短期疗效,但中期和长期疗效尚未得到评估。对于合并轻度DS的椎管狭窄症,减压性椎板切除术联合融合术是否为最佳手术治疗方法尚不清楚。因此,我们评估了接受经单侧入路双侧显微减压且未行融合术的LSS和1级DS患者至少3年的临床疗效和影像学变化。

方法

我们评估了2005年至2007年间由我院一名外科医生连续进行手术的21例患者。术前、出院前及末次随访时测定Oswestry功能障碍指数。使用普通动态X线片测定滑脱百分比。

结果

患者平均年龄、临床和影像学随访时间分别为67岁、49.3个月和18个月。术前、术后即刻及末次随访时的平均Oswestry功能障碍指数分别为59.52±9.00、50.19±7.23和26.19±12.42。然而,1例患者症状加重,随后接受了融合手术。在22个椎体滑脱节段中,15个节段在动态X线片上滑脱百分比无差异,无矢状面活动,但7个节段有矢状面活动。动态X线片上无矢状面活动节段的平均滑脱百分比从13.90±5.41%增加到14.60±5.78%,有矢状面活动节段的平均滑脱百分比从13.12±3.48%增加到18.58±4.55%。

结论

尽管本研究病例系列较小且为回顾性设计且无对照组,但我们的研究表明,LSS和1级DS患者经单侧入路双侧减压术显示出良好的中期临床疗效,尽管滑脱百分比有所增加。然而,术前动态X线片上椎体滑脱节段有矢状面活动的患者比无矢状面活动的患者滑脱增加更明显。因此,经单侧入路双侧减压术可能会加重术前动态X线片有矢状面活动患者的不稳定相关症状,且需要比本研究更长时间的随访。

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