白色念珠菌和细菌性阴道病可在巴氏涂片中共存。

Candida albicans and bacterial vaginosis can coexist on Pap smears.

作者信息

Wei Qingzhu, Fu Bo, Liu Jianghuan, Zhang Zhixiong, Zhao Tong

机构信息

Department of Pathology at The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.

出版信息

Acta Cytol. 2012;56(5):515-9. doi: 10.1159/000339155. Epub 2012 Sep 27.

DOI:10.1159/000339155

PMID:23075892

Abstract

OBJECTIVE

The aim of our study was to study the relationship of blastospores and pseudohyphae in Papanicolaou (Pap) smears and Nugent scores for bacterial vaginosis (BV).

STUDY DESIGN

A total of 471 Pap smears with Candida albicans were reviewed. The presence of blastospores and pseudohyphae was established. The Pap smears were restained with the Gram stain method to evaluate the bacterial flora according to the Nugent scoring system.

RESULTS

Of the 471 Pap smears, blastospores and pseudohyphae were observed in 62.8% (296/471) and 37.2% (175/471) of the smears, and displayed symptoms in 4.4% (13/296) and 43.4% (76/175), respectively. A significant difference was found between these 2 groups (p < 0.0001). A positive BV Nugent score (≥ 7) was found in 22.1% (104/471) of the C. albicans cases. Blastospores and pseudohyphae with BV were 14.2% (42/296) and 35.4% (62/175), respectively. These high Nugent scores indicate statistically significant differences (p < 0.0001).

CONCLUSION

C. albicans and BV can coexist. The presence of blastospores in these C. albicans cases was negatively related to symptoms.

摘要

目的

我们研究的目的是探讨巴氏涂片（Pap涂片）中芽生孢子和假菌丝与细菌性阴道病（BV）的 Nugent评分之间的关系。

研究设计

对471份白色念珠菌感染的Pap涂片进行回顾性分析。确定芽生孢子和假菌丝的存在情况。采用革兰氏染色法对Pap涂片进行复染，根据Nugent评分系统评估细菌菌群。

结果

在471份Pap涂片中，62.8%（296/471）的涂片观察到芽生孢子，37.2%（175/471）的涂片观察到假菌丝，分别有4.4%（13/296）和43.4%（76/175）出现症状。这两组之间存在显著差异（p < 0.0001）。在22.1%（104/471）的白色念珠菌感染病例中发现BV Nugent评分为阳性（≥7）。伴有BV的芽生孢子和假菌丝分别为14.2%（42/296）和35.4%（62/175）。这些高Nugent评分表明存在统计学显著差异（p < 0.0001）。