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危险情况下的酒精使用:对 DSM-IV 和 DSM-5 酒精使用障碍的影响。

Alcohol use in hazardous situations: implications for DSM-IV and DSM-5 alcohol use disorders.

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia.

出版信息

Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1:E228-36. doi: 10.1111/j.1530-0277.2012.01881.x. Epub 2012 Oct 18.

Abstract

BACKGROUND

The use in hazardous situations criterion (hazard) is 1 of 4 criteria related to alcohol abuse in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), and 1 of the 11 criteria related to the new alcohol use disorder (AUD) proposed for DSM-5. The current study aims to evaluate the hazard criterion in the context of both DSM-IV alcohol abuse and DSM-5 AUD.

METHODS

Data came from the 2007 Australian National Survey of Mental Health and Well-Being (n = 8,841) as a stratified, multistage area probability sample of persons aged 16 to 85 years. Logistic regressions were used to: (i) compare the clinical characteristics of those with alcohol abuse including hazard and those with alcohol abuse because of other criteria; (ii) investigate the relationship between the hazard criterion and indices of socioeconomic status (SES); and (iii) investigate the effect of eliminating the hazard criterion on the epidemiology and correlates of the proposed DSM-5 AUD diagnosis.

RESULTS

When compared with the other abuse subgroup, those with abuse including hazard (irrespective of other abuse criteria endorsed) were more likely to report another drug use disorder. The 2 abuse subgroups could not be differentiated by any other clinical characteristics. There were no systematic relationships between the hazard criterion and indices of SES. The elimination of the hazard criterion would lead to a considerable decrease in the prevalence of AUD, with those no longer receiving a diagnosis more likely to be young males with drug use disorders and suicidal behaviors.

CONCLUSIONS

The current study failed to replicate previous analyses that indicated problems with the hazard criterion when assessed in the U.S. population. Many of the problems identified in the hazard criterion appear to be due to operationalizations of this criterion that includes items specifically related to drink-driving. The current results indicate that the elimination of the hazard criterion would lead to a considerable decline in the prevalence of DSM-5 AUD and risk excluding a potentially clinically significant subtype of AUD from future diagnosis.

摘要

背景

在《精神障碍诊断与统计手册》第四版(DSM-IV)中,与酒精滥用相关的 4 个标准之一和与 DSM-5 中新提出的酒精使用障碍(AUD)相关的 11 个标准之一是危险情况标准(hazard)。本研究旨在评估危险标准在 DSM-IV 酒精滥用和 DSM-5 AUD 两方面的应用。

方法

数据来自于 2007 年澳大利亚国家心理健康与幸福感调查(n = 8841),这是一项对 16 至 85 岁人群进行分层、多阶段区域概率抽样的研究。采用逻辑回归分析:(i)比较包含危险标准和其他标准的酒精滥用患者的临床特征;(ii)调查危险标准与社会经济地位(SES)指数之间的关系;(iii)调查消除危险标准对 DSM-5 AUD 诊断的流行病学和相关性的影响。

结果

与其他滥用亚组相比,包含危险标准(无论是否有其他滥用标准)的滥用患者更有可能报告其他药物使用障碍。这两个滥用亚组无法通过任何其他临床特征来区分。危险标准与 SES 指数之间没有系统的关系。消除危险标准将导致 AUD 的患病率显著下降,那些不再接受诊断的人更有可能是年轻男性,伴有药物使用障碍和自杀行为。

结论

本研究未能复制先前在美国人群中进行的表明危险标准存在问题的分析。危险标准中存在的许多问题似乎是由于该标准的操作化,包括与酒后驾车相关的特定项目。目前的结果表明,消除危险标准将导致 DSM-5 AUD 的患病率显著下降,并可能将一种潜在具有临床意义的 AUD 亚型排除在未来的诊断之外。

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