Royal Prince Alfred Hospital Royal North Shore Hospital, Sydney, Australia.
Dig Endosc. 2012 Nov;24(6):448-51. doi: 10.1111/j.1443-1661.2012.01302.x. Epub 2012 Apr 8.
Diagnostic yield of endoscopic ultrasound (EUS)-fine-needle aspiration (FNA) varies depending on the equipment used and the site targeted. Multiple needle passes are usually required to obtain a diagnosis. A new needle incorporating a side-port carries a theoretical advantage regarding acquisition of cytological material. The aim of the study was to demonstrate the safety and efficacy of the Olympus side-port needle in solid upper gastrointestinal indications.
A prospective multicenter evaluation of patients referred for EUS-FNA for solid lesions was performed across six tertiary gastroenterology referral centers in four capital cities in Australia. The main outcome measures include cytological diagnosis, number of needle passes required for diagnosis and complication rates.
Thirty patients (17 men; 13 women) with a mean age of 67.5 years were studied. Indications included pancreatic or biliary mass in 24 patients, retroperitoneal or periduodenal mass in 2, enlarged lymph node in 2, a gastric submucosal tumor in 1 and a subcarinal mass in 1. The mean size of the lesions was 3.47 cm (range, 0.5-8 cm). All but one case had a diagnosis made (96.7%). The mean number of passes required to reach a diagnosis was 1.7. In neoplastic lesions the diagnosis was made with a mean of 1.6 passes. No complications were encountered.
The new EUS-FNA needle with side port appears effective and safe in solid upper gastrointestinal EUS-FNA indications.
内镜超声（EUS）-细针抽吸（FNA）的诊断率取决于所用设备和目标部位。通常需要多次穿刺才能获得诊断。一种新的带有侧孔的针在获取细胞学标本方面具有理论优势。本研究旨在证明 Olympus 侧孔针在固体上消化道适应证中的安全性和有效性。
对六家澳大利亚四个首府的三级胃肠病学转诊中心的因固体病变接受 EUS-FNA 的患者进行了前瞻性多中心评估。主要观察指标包括细胞学诊断、达到诊断所需的穿刺次数和并发症发生率。
研究纳入 30 例（男 17 例，女 13 例）年龄平均 67.5 岁的患者。适应证包括胰腺或胆道肿块 24 例，腹膜后或十二指肠周围肿块 2 例，淋巴结肿大 2 例，胃黏膜下肿瘤 1 例，隆突下肿块 1 例。病变平均大小为 3.47cm（范围 0.5-8cm）。除 1 例外，所有患者均获得诊断（96.7%）。达到诊断所需的平均穿刺次数为 1.7 次。在肿瘤性病变中，平均穿刺 1.6 次即可做出诊断。未发生任何并发症。
新型 EUS-FNA 带侧孔针在上消化道 EUS-FNA 适应证中具有有效性和安全性。
