Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Mov Disord. 2012 Nov;27(13):1690-3. doi: 10.1002/mds.25184. Epub 2012 Oct 18.
Freezing of gait (FOG) is defined as an episodic inability to generate effective stepping in the absence of any known cause other than parkinsonism or high-level gait disorders.
We present a 59-year-old male with acute, progressive episodes of FOG. Imaging studies revealed a dural arteriovenous fistula (DAVF) associated with edema of the globus pallidus interna (GPi). Cerebral angiography confirmed the diagnosis of DAVF and demonstrated an occluded straight sinus and a retrograde blood flow of deep cerebral veins.
After endovascular closure of the DAVF, a major improvement of FOG was observed concomitant with striking near resolution of GPi congestion.
This reversal of the clinical course, correlated with changes in imaging studies, suggests a major role of the GPi in the pathology of FOG.
冻结步态（FOG）定义为在没有帕金森病或高级步态障碍等已知原因的情况下，出现间歇性无法有效行走。
我们介绍了一位 59 岁的男性，他出现了急性、进行性的 FOG 发作。影像学研究显示硬脑膜动静脉瘘（DAVF）伴有内苍白球水肿。脑血管造影证实了 DAVF 的诊断，并显示直窦闭塞和深部脑静脉逆行血流。
DAVF 血管内闭合后，FOG 明显改善，同时内苍白球充血明显缓解。
这种临床病程的逆转，与影像学研究的变化相关，提示 GPi 在 FOG 病理中的重要作用。
