Erdem Alim, Uenishi Masahiro, Matsumoto Kazuo, Küçükdurmaz Zekeriya, Kato Ritsushi, Sahin Safak, Yazıcı Mehmet
Cardiology Department, Abant Izzet Baysal University, Bolu, Turkey.
J Interv Card Electrophysiol. 2012 Dec;35(3):253-8. doi: 10.1007/s10840-012-9741-y. Epub 2012 Oct 19.
Metabolic syndrome (MetS) prevalence shows some differences at various regions of the world in terms of race and ethnicity. The cardiac autonomic functions between Turkish and Japanese MetS patients with heart rate turbulence (HRT) and heart rate variability (HRV) were compared as the aim of this study.
This study consists of 149 nondiabetic subjects with MetS. All patients were further classified into subgroups based on ethnicity (76 from Turkey, 73 from Japan). Twenty-four-hour ambulatory Holter ECG recording was applied to all subjects whose HRV and HRT (total onset (TO), total slope (TS)) parameters were analyzed.
The waist circumference was the only demographic parameter that was significantly different between the Turkish and Japanese patients with MetS (99.31 ± 6.12 vs 91.12 ± 6.89 for men and 91.48 ± 7.45 vs 86.26 ± 5.78 for woman; p < 0.001 and <0.001). There was a significant difference between Turkish and Japanese patients with MetS in terms of the HRT values. (TO Turkish, 0.77 ± 0.19 %; TO Japanese, 0.49 ± 1.03 %, p = 0.031; TS Turkish, 1.93 ± 1.26; TS Japanese, 2.44 ± 1.37, p = 0.041, respectively). As for HRV parameters, standard deviation of all NN intervals index was only different between Turkish and Japanese patients with MetS (90.79 ± 58.94, 128.18 ± 105.30; p = 0.034, respectively).
HRT and some HRV scores of ethnic Turkish MetS patients are worse than the scores of ethnic Japan MetS patients. We think that these differences are related to the central obesity.
代谢综合征（MetS）的患病率在世界不同地区因种族和民族而存在一些差异。本研究旨在比较土耳其和日本患有心率震荡（HRT）和心率变异性（HRV）的MetS患者的心脏自主神经功能。
本研究纳入了149例非糖尿病MetS患者。所有患者根据种族进一步分为亚组（76例来自土耳其，73例来自日本）。对所有受试者进行24小时动态心电图记录，并分析其HRV和HRT（总起始（TO）、总斜率（TS））参数。
腰围是土耳其和日本MetS患者之间唯一有显著差异的人口统计学参数（男性分别为99.31±6.12和91.12±6.89；女性分别为91.48±7.45和86.26±5.78；p<0.001和<0.001）。土耳其和日本MetS患者在HRT值方面存在显著差异。（TO土耳其患者为0.77±0.19%；TO日本患者为0.49±1.03%，p=0.031；TS土耳其患者为1.93±1.26；TS日本患者为2.44±1.37，p=0.041）。至于HRV参数，所有NN间期指数的标准差仅在土耳其和日本MetS患者之间存在差异（分别为90.79±58.94、128.18±105.30；p=0.034）。
土耳其族MetS患者的HRT和一些HRV评分比日本族MetS患者的评分差。我们认为这些差异与中心性肥胖有关。
