Grabtchak Serge, Whelan William M
Department of Physics, University of Prince Edward Island, Charlottetown, PEI C1A4P3, Canada ; Department of Electrical and Computer Engineering, Dalhousie University, Halifax, NS B3J1Z1, Canada ; Department of Physics, Dalhousie University, Halifax, NS B3H3J5, Canada.
Biomed Opt Express. 2012 Oct 1;3(10):2371-80. doi: 10.1364/BOE.3.002371. Epub 2012 Sep 4.
We present a new method for extracting the effective attenuation coefficient and the diffusion coefficient from relative spectrally resolved cw radiance measurements using the diffusion approximation. The method is validated on both simulated and experimental radiance data sets using Intralipid-1% as a test platform. The effective attenuation coefficient is determined from a simple algebraic expression constructed from a ratio of two radiance measurements at two different source-detector separations and the same 90° angle. The diffusion coefficient is determined from another ratio constructed from two radiance measurements at two angles (0° and 180°) and the same source-detector separation. The conditions of the validity of the method as well as possible practical applications are discussed.
我们提出了一种新方法,该方法利用扩散近似从相对光谱分辨的连续波辐射率测量中提取有效衰减系数和扩散系数。使用1%的英脱利匹特作为测试平台,在模拟和实验辐射率数据集上对该方法进行了验证。有效衰减系数由一个简单的代数表达式确定,该表达式由在两个不同源 - 探测器间距和相同90°角度下的两个辐射率测量值之比构成。扩散系数由另一个比值确定,该比值由在两个角度(0°和180°)和相同源 - 探测器间距下的两个辐射率测量值构成。讨论了该方法的有效性条件以及可能的实际应用。