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在浑浊介质的光学测量中,用金纳米颗粒作为局域吸收体标记光子。

Tagging photons with gold nanoparticles as localized absorbers in optical measurements in turbid media.

作者信息

Grabtchak Serge, Callaghan Kristen B, Whelan William M

机构信息

Department of Physics, University of Prince Edward Island, Charlottetown, PEI C1A4P3, Canada ; Departments of Electrical and Computer Engineering, and Physics, Dalhousie University, Halifax, NS B3H3J5, Canada.

Department of Physics, University of Prince Edward Island, Charlottetown, PEI C1A4P3, Canada.

出版信息

Biomed Opt Express. 2013 Nov 25;4(12):2989-3006. doi: 10.1364/BOE.4.002989. eCollection 2013.

DOI:10.1364/BOE.4.002989
PMID:24409396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3862156/
Abstract

We analyze a role of a localized inclusion as a probe for spatial distributions of migrating photons in turbid media. We present new experimental data and two-dimensional analysis of radiance detection of a localized absorptive inclusion formed by gold nanoparticles in Intralipid-1% when the target is translated along the line connecting the light source and detector. Data are analyzed using the novel analytical expression for the relative angular photon distribution function for radiance developed by extending the perturbation approach for fluence. Obtained photon maps allow predicting conditions for detectability of inclusions for which proximity to the detector is essential.

摘要

我们分析了局部内含物作为浑浊介质中迁移光子空间分布探测器的作用。我们展示了新的实验数据以及当目标物沿着连接光源和探测器的直线移动时,对由金纳米颗粒在1%的英脱利匹特中形成的局部吸收性内含物的辐亮度检测的二维分析。使用通过扩展通量微扰方法得到的关于辐亮度的相对角光子分布函数的新解析表达式来分析数据。获得的光子图能够预测内含物的可检测条件,对于这些条件而言,靠近探测器至关重要。

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Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts.基于全吸收物体的漫射光学成像的体模,第 1 部分:基本概念。
J Biomed Opt. 2013 Jun;18(6):066014. doi: 10.1117/1.JBO.18.6.066014.
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5
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Biomed Opt Express. 2012 Oct 1;3(10):2371-80. doi: 10.1364/BOE.3.002371. Epub 2012 Sep 4.
6
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