Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Radiat Oncol. 2012 Oct 22;7:174. doi: 10.1186/1748-717X-7-174.
Over the past 20 years, several proton beam treatment programs have been implemented throughout the United States. Increasingly, the number of new programs under development is growing. Proton beam therapy has the potential for improving tumor control and survival through dose escalation. It also has potential for reducing harm to normal organs through dose reduction. However, proton beam therapy is more costly than conventional x-ray therapy. This increased cost may be offset by improved function, improved quality of life, and reduced costs related to treating the late effects of therapy. Clinical research opportunities are abundant to determine which patients will gain the most benefit from proton beam therapy. We review the clinical case for proton beam therapy. SUMMARY SENTENCE: Proton beam therapy is a technically advanced and promising form of radiation therapy.
在过去的 20 年中，美国已经实施了多个质子束治疗计划。越来越多的新计划正在开发中。质子束治疗有可能通过提高剂量来提高肿瘤控制和生存率。它还有可能通过减少剂量来降低对正常器官的伤害。然而，质子束治疗比传统的 X 射线治疗更昂贵。这种增加的成本可能会被功能的改善、生活质量的提高以及治疗治疗后期效应相关成本的降低所抵消。有大量的临床研究机会来确定哪些患者将从质子束治疗中获益最大。我们回顾了质子束治疗的临床案例。总结句：质子束治疗是一种技术先进且有前途的放射治疗形式。
